R
Robert J. Christy
Researcher at United States Department of the Army
Publications - 106
Citations - 5679
Robert J. Christy is an academic researcher from United States Department of the Army. The author has contributed to research in topics: Wound healing & Stem cell. The author has an hindex of 30, co-authored 98 publications receiving 4935 citations. Previous affiliations of Robert J. Christy include Johns Hopkins University School of Medicine & University of Texas Health Science Center at San Antonio.
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Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest.
TL;DR: Results suggest that GKLF is potentially a negative regulator of cell growth in tissues such as the gut mucosa, where cell proliferation is intimately coupled to growth arrest and differentiation.
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Burn wound healing and treatment: review and advancements
Matthew P. Rowan,Leopoldo C. Cancio,Eric A. Elster,David M. Burmeister,Lloyd F. Rose,Shanmugasundaram Natesan,Rodney K. Chan,Robert J. Christy,Kevin K. Chung,Kevin K. Chung +9 more
TL;DR: Recent advancements in the care of burn patients with a focus on the pathophysiology and treatment of burn wounds are reviewed, including improvements in patient stabilization and care.
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Differentiation-induced gene expression in 3T3-L1 preadipocytes: CCAAT/enhancer binding protein interacts with and activates the promoters of two adipocyte-specific genes.
Robert J. Christy,Vincent W. Yang,James M. Ntambi,Deborah E. Geiman,William H. Landschulz,A. D. Friedman,Yusaku Nakabeppu,T. J. Kelly,M D Lane +8 more
TL;DR: Several lines of evidence indicate that the differentiation-induced nuclear factor is CCAAT/enhancer binding protein (C/EBP), a DNA-binding protein first isolated from rat liver.
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CCAAT/enhancer binding protein gene promoter: binding of nuclear factors during differentiation of 3T3-L1 preadipocytes.
TL;DR: DNase I cleavage-inhibition patterns (footprinting) of the C/EBP gene promoter by nuclear factors from differentiated and undifferentiated 3T3-L1 cells identified two sites of differential factor binding.
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Differentiation-induced gene expression in 3T3-L1 preadipocytes. Characterization of a differentially expressed gene encoding stearoyl-CoA desaturase.
James M. Ntambi,S A Buhrow,Klaus H. Kaestner,Robert J. Christy,Eric Sibley,Thomas J. Kelly,M D Lane +6 more
TL;DR: Analysis of the nucleotide and amino acid sequences of both cDNA and genomic clones revealed that the mouse stearoyl-CoA desaturase is an enzyme known to be expressed upon differentiation of 3T3-L1 preadipocytes, suggesting that the SCD promoter region contains elements that mediate the response to adipogenic agents which induce differentiation.