R
Robert M. Craig
Researcher at Northwestern University
Publications - 186
Citations - 8865
Robert M. Craig is an academic researcher from Northwestern University. The author has contributed to research in topics: Hematopoietic stem cell transplantation & Actin. The author has an hindex of 40, co-authored 183 publications receiving 8614 citations. Previous affiliations of Robert M. Craig include Cleveland Clinic & Johns Hopkins University.
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Journal ArticleDOI
Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis
Robert G. Knodell,Kamal G. Ishak,William C. Black,Thomas S. Chen,Robert M. Craig,Neil Kaplowitz,T Kiernan,Jerome Wollman +7 more
TL;DR: A Histology Activity Index has been developed which generates a numerical score for liver biopsy specimens obtained from patients with asymptomatic chronic active hepatitis that provides definitive endpoints for statistical analysis of serial changes in liver histology and offers an alternative to the use of conventional pathological descriptions.
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Autologous non-myeloablative haemopoietic stem-cell transplantation compared with pulse cyclophosphamide once per month for systemic sclerosis (ASSIST): an open-label, randomised phase 2 trial
Richard K. Burt,Sanjiv J. Shah,Karin E. Dill,Thomas H. Grant,Mihai Gheorghiade,James W. Schroeder,Robert M. Craig,Ikuo Hirano,Karin Marshall,Eric Ruderman,Borko Jovanovic,Francesca Milanetti,Francesca Milanetti,Sandeep Jain,Kristin Boyce,Amy Morgan,James C. Carr,Walter G. Barr +17 more
TL;DR: Non-myeloablative autologous HSCT improves skin and pulmonary function in patients with systemic sclerosis for up to 2 years and is preferable to the current standard of care, but longer follow-up is needed.
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Clinical Applications of Blood-Derived and Marrow-Derived Stem Cells for Nonmalignant Diseases
Richard K. Burt,Yvonne Loh,William H. Pearce,Nirat Beohar,Walter G. Barr,Robert M. Craig,Yanting Wen,Jonathan A. Rapp,John A. Kessler +8 more
TL;DR: Stem cells harvested from blood or marrow, whether administered as purified HSCs or mesenchymal stem cells or as an unmanipulated or unpurified product can provide disease-ameliorating effects in some autoimmune diseases and cardiovascular disorders.
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A Cystic Fibrosis Bronchial Epithelial Cell Line: Immortalization by Adeno-12-SV40 Infection
Pamela L. Zeitlin,Luo Lu,J. Rhim,Garry R. Cutting,G. Stetten,K. A. Kieffer,Robert M. Craig,William B. Guggino +7 more
TL;DR: The immortalized cell line was created from a primary culture of bronchial epithelia isolated from a patient with cystic fibrosis and transformed with a hybrid virus, adeno-12-SV40, which has been used successfully on a number of different human epithelial tissues.
Journal ArticleDOI
Autologous hematopoietic stem cell transplantation in patients with refractory Crohn's disease
Yu Oyama,Robert M. Craig,Ann E. Traynor,Kathleen Quigley,Laisvyde Statkute,Amy L. Halverson,Mary Brush,Larissa Verda,Barbara Kowalska,Nela Krosnjar,Morris Kletzel,Peter F. Whitington,Richard K. Burt +12 more
TL;DR: Autologous HSCT may be performed safely and has a marked salutary effect on CD activity, and a randomized study will be needed to confirm the efficacy of this therapy.