R
Robert M. Williams
Researcher at Colorado State University
Publications - 327
Citations - 11303
Robert M. Williams is an academic researcher from Colorado State University. The author has contributed to research in topics: Enantioselective synthesis & Total synthesis. The author has an hindex of 54, co-authored 327 publications receiving 10588 citations. Previous affiliations of Robert M. Williams include University of Colorado Boulder & University of Colorado Denver.
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Chemistry and biology of the tetrahydroisoquinoline antitumor antibiotics.
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Asymmetric synthesis of arylglycines
TL;DR: In this paper, either cuprate or Friedel-Crafts couplings to chiral bromoglycinates were employed to unmask the oxazinone chiral auxiliary providing the free α-amino acids.
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Asymmetric synthesis of monosubstituted and .alpha.,.alpha.-disubstituted .alpha.-amino acids via diastereoselective glycine enolate alkylations
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Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase
TL;DR: A PCR-based differential display-cloning approach yielded a family of related cytochrome P450 genes, one of which was assigned as a taxane 10β-hydroxylase by functional expression in yeast and validates this strategy for elucidating the oxygenation steps of taxane diterpenoid (taxoid) metabolism.