R
Robert N. Baldassano
Researcher at Children's Hospital of Philadelphia
Publications - 326
Citations - 37278
Robert N. Baldassano is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 72, co-authored 301 publications receiving 31551 citations. Previous affiliations of Robert N. Baldassano include Seattle Children's & University of California, Los Angeles.
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Journal ArticleDOI
Inflammatory bowel disease: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition.
S H Murch,Robert N. Baldassano,Hans A. Büller,Simon Chin,Anne M. Griffiths,Hans Hildebrand,Clara Jasinsky,Tse Kong,David D. Moore,Marina Orsi +9 more
TL;DR: This work aims to establish an international paediatric IBD clinical trials bureau, facilitate the rapid assessment of novel agents in paediatric practice, and identify the factors that lead to optimal delivery of high-quality care.
Journal ArticleDOI
Increases in IGF-1 After Anti-TNF-α Therapy Are Associated With Bone and Muscle Accrual in Pediatric Crohn Disease.
Mark D. DeBoer,Arthur M. Lee,Kirabo Herbert,Jin Long,Meena Thayu,Lindsay M. Griffin,Robert N. Baldassano,Lee A. Denson,Babette S. Zemel,Michelle R. Denburg,Rita Herskovitz,Mary B. Leonard +11 more
TL;DR: Short-term improvements in IGF-1 z scores predicted recovery of bone and muscle outcomes following initiation of anti-TNF-α therapy in pediatric CD, and suggest that disease effects on growth hormone metabolism contribute to musculoskeletal deficits in CD.
Journal ArticleDOI
Phase I trial of sargramostim in pediatric Crohn's disease
Judith R. Kelsen,Joel R. Rosh,Mel Heyman,Harland S. Winter,George D. Ferry,Stanley A. Cohen,Petar Mamula,Robert N. Baldassano +7 more
TL;DR: Sargramostim at both 4 and 6 mg/kg was well tolerated and PK analysis suggested dose proportionality unaffected by CS exposure, but further trials are needed to assess efficacy.
Journal ArticleDOI
Remodeling of the maternal gut microbiome during pregnancy is shaped by parity.
Alexander S. F. Berry,Alexander S. F. Berry,Meghann K. Pierdon,Ana M. Misic,Megan C. Sullivan,Kevin O'Brien,Ying Chen,Samuel J. Murray,Lydia A. Ramharack,Robert N. Baldassano,Thomas D. Parsons,Daniel P. Beiting +11 more
TL;DR: For instance, the authors found that parity was associated with the relative abundance of several bacterial species, including Treponema bryantii, Lactobacillus amylovorus, and Lachancella reuteri.
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The role of monogenic disease in children with very early onset inflammatory bowel disease.
TL;DR: The advances in sequencing technology that have led to identification of novel gene variants associated with disease and potentially new targeted therapeutic options are reviewed to allow for true precision medicine with targeted therapy and improved disease course.