R
Roberta Francesca De Rose
Researcher at Magna Græcia University
Publications - 7
Citations - 247
Roberta Francesca De Rose is an academic researcher from Magna Græcia University. The author has contributed to research in topics: Thyroid cancer & Thyroid carcinoma. The author has an hindex of 6, co-authored 7 publications receiving 196 citations. Previous affiliations of Roberta Francesca De Rose include Health Science University.
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Fibronectin-1 expression is increased in aggressive thyroid cancer and favors the migration and invasion of cancer cells.
Marialuisa Sponziello,Francesca Rosignolo,Marilena Celano,Valentina Maggisano,Valeria Pecce,Roberta Francesca De Rose,Giovanni Enrico Lombardo,Cosimo Durante,Sebastiano Filetti,G. Damante,Diego Russo,Stefania Bulotta +11 more
TL;DR: expression levels of markers of epithelial-to-mesenchymal transition (EMT) in several papillary thyroid carcinomas (PTCs) and the relation with tumor genotypes and clinicopathological characteristics indicate that FN1 overexpression is an important determinant of thyroid cancer aggressiveness.
Journal ArticleDOI
Flavonoid Fraction of Citrus reticulata Juice Reduces Proliferation and Migration of Anaplastic Thyroid Carcinoma Cells.
Marilena Celano,Valentina Maggisano,Roberta Francesca De Rose,Stefania Bulotta,Jessica Maiuolo,Michele Navarra,Diego Russo +6 more
TL;DR: It is demonstrated that the flavonoid fraction of mandarin juice exerts in vitro antiproliferative effects on ATC cells, associated with a reduction of migration, suggesting for such a functional food a potential use as adjuvant in the treatment of thyroid cancer.
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PDE5 expression in human thyroid tumors and effects of PDE5 inhibitors on growth and migration of cancer cells.
Marialuisa Sponziello,Antonella Verrienti,Francesca Rosignolo,Roberta Francesca De Rose,Valeria Pecce,Valentina Maggisano,Cosimo Durante,Stefania Bulotta,Giuseppe Damante,Laura Giacomelli,Cira Di Gioia,Sebastiano Filetti,Diego Russo,M. Celano +13 more
TL;DR: These findings demonstrate for the first time an overexpression of PDE5 in PTCs, and the ability of Sildenafil and tadalafil to block the proliferation of thyroid cancer cells in culture, suggesting that specific inhibition of Pde5 may be proposed for the treatment of these tumors.
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PDE5 Inhibitors-Loaded Nanovesicles: Physico-Chemical Properties and In Vitro Antiproliferative Activity.
Roberta Francesca De Rose,Maria Chiara Cristiano,Marilena Celano,Valentina Maggisano,Ada Vero,Giovanni Enrico Lombardo,Martina Di Francesco,Donatella Paolino,Diego Russo,Donato Cosco +9 more
TL;DR: It is demonstrated that nanoliposomes increase the antiproliferative activity of phosphodiesterase-5 inhibitors, providing a useful novel formulation for the treatment of thyroid carcinoma.
Journal ArticleDOI
Normocaloric Diet Restores Weight Gain and Insulin Sensitivity in Obese Mice.
Giovanni Enrico Lombardo,Biagio Arcidiacono,Roberta Francesca De Rose,Saverio Massimo Lepore,Nicola Costa,Tiziana Montalcini,Antonio Brunetti,Diego Russo,Giovambattista De Sarro,Marilena Celano +9 more
TL;DR: Results indicate that obesity-related insulin resistance may be rescued by shifting from HFD to NCD, and a significant reduction of body weight was found after the transition from high to normal fat diet, and this decrease correlated well with an improvement in insulin sensitivity.