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Roberta Libener
Researcher at University of Genoa
Publications - 70
Citations - 1699
Roberta Libener is an academic researcher from University of Genoa. The author has contributed to research in topics: Mesothelioma & Medicine. The author has an hindex of 20, co-authored 55 publications receiving 1429 citations.
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Journal ArticleDOI
The use of autologous platelet gel to treat difficult‐to‐heal wounds: a pilot study
Laura Mazzucco,Dante Medici,Massimo Serra,Renzo Panizza,Giorgio Rivara,Sara Orecchia,Roberta Libener,Elena Cattana,A. Levis,Pier Giacomo Betta,Piero Borzini +10 more
TL;DR: The aim of this study was to verify the effectiveness of autologous PLT gel in the treatment of nonhealing skin lesions and to provide tissue regeneration‐inducing GFs.
Journal ArticleDOI
Targeted Next-Generation Sequencing of Cancer Genes in Advanced Stage Malignant Pleural Mesothelioma: A Retrospective Study
Marco Lo Iacono,Valentina Monica,Luisella Righi,Federica Grosso,Roberta Libener,Simona Vatrano,Paolo Bironzo,Silvia Novello,Loredana Musmeci,Marco Volante,Mauro Papotti,Giorgio V. Scagliotti +11 more
TL;DR: Next-generation sequencing was applied to a relatively large retrospective series of MPM using formalin-fixed, paraffin-embedded archival material and results indicate a complex mutational landscape with a higher number of genetic variations in the p53/DNA repair and phosphatidylinositol 3-kinase pathways, some of them with prognostic value.
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SV40 replication in human mesothelial cells induces HGF/Met receptor activation: A model for viral-related carcinogenesis of human malignant mesothelioma
Paola Cacciotti,Roberta Libener,Pier-Giacomo Betta,Fernanda Martini,Camillo Porta,Antonio Domenico Procopio,Luigi Strizzi,Lorenza Penengo,Mauro Tognon,Luciano Mutti,Giovanni Gaudino +10 more
TL;DR: SV40 replicates in HMC and infects the adjacent HMC, inducing an HGF-dependent Met activation and cell-cycle progression into S phase, which may explain how a limited number of SV40-positive cells may be sufficient to direct noninfected HMC toward malignant transformation.
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Cancer testis antigens expression in mesothelioma: role of DNA methylation and bioimmunotherapeutic implications.
Luca Sigalotti,Sandra Coral,Maresa Altomonte,L Natali,Giovanni Gaudino,Paola Cacciotti,Roberta Libener,Francesca Colizzi,Giovina Vianale,Fernanda Martini,Mauro Tognon,Achim A. Jungbluth,Jonathan Cebon,Eugene Maraskovsky,Luciano Mutti,Michele Maio +15 more
TL;DR: The findings strongly suggest that cancer/testis antigens-based immunotherapy may represent a suitable therapeutic approach to malignant mesothelioma, and foresee the clinical use of 5-aza-2′-deoxycytidine to design new chemo-immunotherapeutic strategies in malignant asbestos patients.
Journal ArticleDOI
SV40 Enhances the Risk of Malignant Mesothelioma among People Exposed to Asbestos: A Molecular Epidemiologic Case-Control Study
Alfonso Cristaudo,Rudy Foddis,Agnese Vivaldi,R Buselli,Vittorio Gattini,Giovanni Guglielmi,Francesca Cosentino,Franco Ottenga,Eugenio Ciancia,Roberta Libener,Rosangela Filiberti,Monica Neri,PierGiacoino Betta,Mauro Tognon,Luciano Mutti,Riccardo Puntoni +15 more
TL;DR: The results suggest that SV40 increases the risk of MM among individuals exposed to asbestos.