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Eugene Maraskovsky
Researcher at CSL Limited
Publications - 135
Citations - 18556
Eugene Maraskovsky is an academic researcher from CSL Limited. The author has contributed to research in topics: Antigen & Immune system. The author has an hindex of 60, co-authored 135 publications receiving 17880 citations. Previous affiliations of Eugene Maraskovsky include University of Melbourne & Ludwig Institute for Cancer Research.
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Early Lymphocyte Expansion Is Severely Impaired in Interleukin 7 Receptor-deficient Mice By Jacques J. Peschon, Philip J. Morrissey, Kenneth H. Grabstein,
Fred J. Ramsde,Eugene Maraskovsky,Brian C. Gliniak,Linda S. Park,Steven F. Ziegler,Doughs E. Williams,Carol B. Ware,Jeff D. Meyer,Barry L. Davison +8 more
TL;DR: Significantly, these studies indicate that the phase of thymocyte expansion occurring before the onset of T cell receptor gene rearrangement is critically dependent upon, and mediated by the high affinity receptor for IL-7.
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Dramatic increase in the numbers of functionally mature dendritic cells in Flt3 ligand-treated mice: multiple dendritic cell subpopulations identified.
Eugene Maraskovsky,Kenneth Brasel,M Teepe,E. Roux,Stewart D. Lyman,Ken Shortman,H.J. McKenna +6 more
TL;DR: Dendritic cells exhibited veiled and dendritic processes and were as efficient as rare, mature DC isolated from the spleens of untreated mice at presenting allo-Ag or soluble Ag to T cells, or in priming an Ag-specific T cell response in vivo.
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Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.
Nadine Fernandez,A. Lozier,Caroline Flament,Paola Ricciardi-Castagnoli,Dominique Bellet,Mark Suter,Michel Perricaudet,Thomas Tursz,Eugene Maraskovsky,Laurence Zitvogel +9 more
TL;DR: In mice with MHC class I-negative tumors, adoptively transferred- or Flt3 ligand-expanded DC promoted NK cell-dependent anti-tumor effects and are involved in the interaction between innate and adaptive immune responses.
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Distinct dendritic cell subsets differentially regulate the class of immune response in vivo
Bali Pulendran,J. L. Smith,G. Caspary,Kenneth Brasel,D. Pettit,Eugene Maraskovsky,C. R. Maliszewski +6 more
TL;DR: It is suggested that distinct DC subsets have strikingly different influences on the type of immune response generated in vivo and may thus be targets for pharmacological intervention.
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Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells.
Hilary J. McKenna,Kim L. Stocking,Robert E. Miller,Kenneth Brasel,Thibaut De Smedt,Eugene Maraskovsky,Charles R. Maliszewski,David H. Lynch,Jeffrey B. Smith,Bali Pulendran,Eileen R. Roux,Mark Teepe,Stewart D. Lyman,Jacques J. Peschon +13 more
TL;DR: It is concluded that flt3L has an important role in the expansion of early hematopoietic progenitors and in the generation of mature peripheral leukocytes.