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Roberta Visconti
Researcher at University of Naples Federico II
Publications - 68
Citations - 4451
Roberta Visconti is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Gene & Phosphorylation. The author has an hindex of 33, co-authored 61 publications receiving 4144 citations. Previous affiliations of Roberta Visconti include National Research Council & Mediterranea University of Reggio Calabria.
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Journal Article
High level expression of the HMGI (Y) gene during embryonic development.
Gennaro Chiappetta,Virginia Avantaggiato,Roberta Visconti,Monica Fedele,Sabrina Battista,Francesco Trapasso,Bianca Maria Merciai,Vincenzo Fidanza,Vincenzo Giancotti,Massimo Santoro,Antonio Simeone,Alfredo Fusco +11 more
TL;DR: It is demonstrated that the HMGI (Y) gene is expressed at very low levels in normal adult tissues, whereas in embryonic tissues it is expressed in high levels comparable to those detected in neoplastic tissues.
Journal Article
New insights on oxidative stress in cancer.
Roberta Visconti,Domenico Grieco +1 more
TL;DR: Recent findings that relate oxidative stress to cancer-associated conditions, such as chronic inflammation, steroid hormone signaling and altered chromosome segregation, are highlighted and how these studies may identify new targets for the development of drugs and strategies for cancer prevention and cure is discussed.
Journal Article
RET/PTC oncogene activation is an early event in thyroid carcinogenesis
Giuseppe Viglietto,Gennaro Chiappetta,F. J. Martinez-Tello,Fukunaga Fh,Giovanni Tallini,Rigopoulou D,Roberta Visconti,Mastro A,M Santoro,Alfredo Fusco +9 more
TL;DR: It is demonstrated, by using a combined immunohistochemical and reverse transcriptase-polymerase chain reaction based approach, that RET/PTC activation is present in 11 out of 26 occult thyroid papillary carcinomas analysed and represents an early event in the process of thyroid cell transformation.
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Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes.
Denis Franchimont,Jérôme Galon,Massimo Gadina,Roberta Visconti,Yong Jie Zhou,Martin Aringer,David M. Frucht,George P. Chrousos,John J. O'Shea +8 more
TL;DR: Blocking IL-12-induced Stat4 phosphorylation appears to be a new suppressive action of glucocorticoids on the Th1 cellular immune response and may help explain the glucoc Corticoid-induced shift toward the Th2 humoral immune response.
Journal ArticleDOI
Cell cycle checkpoint in cancer: a therapeutically targetable double-edged sword
TL;DR: Developing concepts on how targeting cell cycle checkpoints may provide substantial improvement to cancer therapy are summarized.