M
Massimo Santoro
Researcher at University of Naples Federico II
Publications - 100
Citations - 9755
Massimo Santoro is an academic researcher from University of Naples Federico II. The author has contributed to research in topics: Thyroid carcinoma & Thyroid. The author has an hindex of 43, co-authored 100 publications receiving 8850 citations.
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Journal ArticleDOI
Revised American thyroid association guidelines for the management of medullary thyroid carcinoma
Samuel A. Wells,Sylvia L. Asa,Henning Dralle,Rossella Elisei,Douglas B. Evans,Robert F. Gagel,Nancy Y. Lee,Andreas Machens,Jeffrey F. Moley,Furio Pacini,Friedhelm Raue,Karin Frank-Raue,Bruce G. Robinson,M. Sara Rosenthal,Massimo Santoro,Martin Schlumberger,Manisha H. Shah,Steven G. Waguespack +17 more
TL;DR: The revised guidelines are focused primarily on the diagnosis and treatment of patients with sporadic medullary thyroid carcinoma (MTC) and hereditary MTC and developed 67 evidence-based recommendations to assist clinicians in the care of Patients with MTC.
Journal ArticleDOI
BRAF Mutations in Thyroid Tumors Are Restricted to Papillary Carcinomas and Anaplastic or Poorly Differentiated Carcinomas Arising from Papillary Carcinomas
Marina N. Nikiforova,Edna Teruko Kimura,Manoj Gandhi,Paul W. Biddinger,Jeffrey A. Knauf,Fulvio Basolo,Zhaowen Zhu,Riccardo Giannini,Giuliana Salvatore,Alfredo Fusco,Massimo Santoro,James A. Fagin,Yuri E. Nikiforov +12 more
TL;DR: BRAF mutations are associated with distinct phenotypical and biological properties of papillary carcinomas and may participate in progression to poorly differentiated and anaplastic carcinomas.
Journal ArticleDOI
MicroRNA deregulation in human thyroid papillary carcinomas
Pierlorenzo Pallante,Rosa Visone,Rosa Visone,Manuela Ferracin,Angelo Ferraro,Mt Berlingieri,Giancarlo Troncone,Gennaro Chiappetta,Cg Liu,Massimo Santoro,Massimo Negrini,Carlo M. Croce,Alfredo Fusco +12 more
TL;DR: Analysis of genome-wide miRNA expression profile in human thyroid papillary carcinomas and functional studies suggest a critical role of miR-221 overexpression in thyroid carcinogenesis suggest miRNA deregulation as an important event in thyroid cell transformation.
Journal ArticleDOI
BAY 43-9006 Inhibition of Oncogenic RET Mutants
Francesca Carlomagno,Suresh Anaganti,Teresa Guida,Giuliana Salvatore,Giancarlo Troncone,Scott Wilhelm,Massimo Santoro +6 more
TL;DR: BAY 43-9006 is a powerful inhibitor of the RET kinase and its potential as a therapeutic tool for RET-positive thyroid tumors, including those expressing V804 mutations merits study.
Journal ArticleDOI
Specific microRNAs are downregulated in human thyroid anaplastic carcinomas.
Rosa Visone,Pierlorenzo Pallante,Andrea Vecchione,Roberto Cirombella,Manuela Ferracin,Angelo Ferraro,Stefano Volinia,Sabrina Coluzzi,Vincenza Leone,Eleonora Borbone,Chang Gong Liu,Fabio Petrocca,Giancarlo Troncone,George A. Calin,Aldo Scarpa,Chiara Colato,Giovanni Tallini,Massimo Santoro,Carlo M. Croce,Alfredo Fusco +19 more
TL;DR: Analysis of the microRNA profile of ATC in comparison to the normal thyroid using a microarray suggests a miR signature associated with ATC and suggests the miR deregulation as an important event in thyroid cell transformation.