R
Roberto Serpe
Researcher at University of Cagliari
Publications - 48
Citations - 2458
Roberto Serpe is an academic researcher from University of Cagliari. The author has contributed to research in topics: Cachexia & Cancer. The author has an hindex of 24, co-authored 48 publications receiving 2245 citations. Previous affiliations of Roberto Serpe include Polaris Industries & University of Barcelona.
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Journal ArticleDOI
Randomized Phase III Clinical Trial of Five Different Arms of Treatment in 332 Patients with Cancer Cachexia
Giovanni Mantovani,Antonio Macciò,Clelia Madeddu,Roberto Serpe,Elena Massa,Mariele Dessì,Filomena Panzone,Paolo Contu +7 more
TL;DR: The most effective treatment in terms of all three primary efficacy endpoints and the secondary endpoints appetite, IL-6, GPS, and ECOG PS score was the combination regimen that included all selected agents.
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A Phase II Study with Antioxidants, Both in the Diet and Supplemented, Pharmaconutritional Support, Progestagen, and Anti-Cyclooxygenase-2 Showing Efficacy and Safety in Patients with Cancer-Related Anorexia/Cachexia and Oxidative Stress
Giovanni Mantovani,Antonio Macciò,Clelia Madeddu,Giulia Gramignano,Maria Rita Lusso,Roberto Serpe,Elena Massa,Giorgio Astara,Laura Deiana +8 more
TL;DR: The efficacy and safety of the integrated treatment based on a pharmaconutritional support, antioxidants, and drugs, all given orally, in a population of advanced cancer patients with cancer-related anorexia/cachexia and oxidative stress were shown to be safe.
Journal ArticleDOI
The cachexia score (CASCO): a new tool for staging cachectic cancer patients
Josep M. Argilés,Francisco J. López-Soriano,Míriam Toledo,Angelica Betancourt,Roberto Serpe,Roberto Serpe,Sílvia Busquets +6 more
TL;DR: The present score will facilitate cachexia staging and will therefore allow for a more adequate therapy and also take into consideration the condition known as pre-cachexia.
Applied nutritional investigation Efficacy of L-carnitine administration on fatigue, nutritional status, oxidative stress, and related quality of life in 12 advanced cancer patients undergoing anticancer therapy
Giulia Gramignano,Maria Rita Lusso,Clelia Madeddu,Elena Massa,Roberto Serpe,Laura Deiana,Giovanna Lamonica,Mariele Dessì,C. Spiga,Giorgio Astara,Antonio Macciò,Giovanni Mantovani +11 more
TL;DR: Improvement of symptoms with respect to fatigue and quality of life in relation to oxidative stress may be explained mainly by an increase in lean body mass, which may be considered the most important nutritional or functional parameter in assessing the cachectic state of patients.
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Early Epirubicin-Induced Myocardial Dysfunction Revealed by Serial Tissue Doppler Echocardiography: Correlation with Inflammatory and Oxidative Stress Markers
Giuseppe Mercuro,Christian Cadeddu,Alessandra Piras,Mariele Dessì,Clelia Madeddu,Martino Deidda,Roberto Serpe,Elena Massa,Giovanni Mantovani +8 more
TL;DR: A phase II, open, nonrandomized trial was carried out in a group of epirubicin-treated patients with cancer at different sites with the aim of detecting early preclinical changes that are predictive of the risk for heart failure as mentioned in this paper.