R
Rockford K. Draper
Researcher at University of Texas at Dallas
Publications - 56
Citations - 2640
Rockford K. Draper is an academic researcher from University of Texas at Dallas. The author has contributed to research in topics: Golgi apparatus & Chinese hamster ovary cell. The author has an hindex of 24, co-authored 56 publications receiving 2516 citations.
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Journal ArticleDOI
Controlled assembly of carbon nanotubes by designed amphiphilic Peptide helices.
Gregg R. Dieckmann,Alan B. Dalton,Paul Johnson,Joselito M. Razal,Jian Chen,Geoff M. Giordano,Edgar Muñoz,Inga H. Musselman,Ray H. Baughman,Rockford K. Draper +9 more
TL;DR: The data presented herein show that the peptide folds into an amphiphilic alpha-helix in the presence of carbon nanotubes and disperses them in aqueous solution by noncovalent interactions with the nanotube surface.
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Thermal ablation of tumor cells with antibody-functionalized single-walled carbon nanotubes
Pavitra Chakravarty,Radu Marches,Neil S. Zimmerman,Austin D. Swafford,Pooja Bajaj,Inga H. Musselman,Paul Pantano,Rockford K. Draper,Ellen S. Vitetta +8 more
TL;DR: This study demonstrates the specific binding of antibody-coupled CNTs to tumor cells in vitro, followed by their highly specific ablation with NIR light.
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The entry of diphtheria toxin into the mammalian cell cytoplasm: evidence for lysosomal involvement
TL;DR: Exposing the toxin to an acidic environment, such as that found within lysosomes, is an important step in the penetration of diphtheria toxin into the cytoplasm.
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Single-walled carbon nanotube interactions with HeLa cells.
Hadi Nayef Yehia,Rockford K. Draper,Carole Mikoryak,Erin Karen Walker,Pooja Bajaj,Inga H. Musselman,Meredith C. Daigrepont,Gregg R. Dieckmann,Paul Pantano +8 more
TL;DR: The combined results indicate that under the sample preparation protocols and assay conditions, CoMoCAT DM-SWNT dispersions are not inherently cytotoxic to HeLa cells.
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Evidence for penetration of diphtheria toxin to the cytosol through a prelysosomal membrane.
TL;DR: The time required for the toxin to encounter a low pH after endocytosis was measured and it was found that acidification occurred within 3 to 4 min after the toxin was internalized into vesicles, consistent with prelysosomal acidification.