R
Roderick I. Mackie
Researcher at University of Illinois at Urbana–Champaign
Publications - 255
Citations - 21175
Roderick I. Mackie is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Rumen & Glycoside hydrolase. The author has an hindex of 69, co-authored 244 publications receiving 18970 citations. Previous affiliations of Roderick I. Mackie include Energy Biosciences Institute & Urbana University.
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Developmental microbial ecology of the neonatal gastrointestinal tract
TL;DR: In this review, the development of the intestinal microbiota is discussed in terms of initial acquisition and subsequent succession of bacteria in human infants and the advantages of modern molecular ecology techniques that provide sensitive and specific, culture-independent evaluation of the gastrointestinal ecosystem are introduced.
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Metagenomic discovery of biomass-degrading genes and genomes from cow rumen.
Matthias Hess,Matthias Hess,Alexander Sczyrba,Alexander Sczyrba,Rob Egan,Rob Egan,Tae-Wan Kim,Harshal A. Chokhawala,Gary P. Schroth,Shujun Luo,Douglas S. Clark,Feng Chen,Feng Chen,Tao Zhang,Tao Zhang,Roderick I. Mackie,Len A. Pennacchio,Len A. Pennacchio,Susannah G. Tringe,Susannah G. Tringe,Axel Visel,Axel Visel,Tanja Woyke,Tanja Woyke,Zhong Wang,Zhong Wang,Edward M. Rubin,Edward M. Rubin +27 more
TL;DR: To characterize biomass-degrading genes and genomes, this work sequenced and analyzed 268 gigabases of metagenomic DNA from microbes adherent to plant fiber incubated in cow rumen and identified 27,755 putative carbohydrate-active genes and expressed 90 candidate proteins, of which 57% were enzymatically active against cellulosic substrates.
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Occurrence and Diversity of Tetracycline Resistance Genes in Lagoons and Groundwater Underlying Two Swine Production Facilities
TL;DR: It is demonstrated that tet genes occur in the environment as a direct result of agriculture and suggested that groundwater may be a potential source of antibiotic resistance in the food chain.
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Fate and transport of antibiotic residues and antibiotic resistance genes following land application of manure waste.
Joanne C. Chee-Sanford,Roderick I. Mackie,Satoshi Koike,Ivan G. Krapac,Yu-Feng Lin,Anthony C. Yannarell,Scott Maxwell,Rustam Aminov +7 more
TL;DR: Findings are discussed that address aspects of the fate, transport, and persistence of antibiotics and antibiotic resistance genes in natural environments, with emphasis on mechanisms pertaining to soil environments following land application of animal waste effluent.
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Molecular Ecology of Tetracycline Resistance: Development and Validation of Primers for Detection of Tetracycline Resistance Genes Encoding Ribosomal Protection Proteins
TL;DR: Phylogenetic analysis of tetracycline resistance genes encoding the ribosomal protection proteins (RPPs) revealed the monophyletic origin of these genes, which is the first demonstration of the applicability of molecular ecology techniques to estimation of the gene pool and the flux of antibiotic resistance genes in production animals.