R
Rodolphe Poupardin
Researcher at Paracelsus Private Medical University of Salzburg
Publications - 15
Citations - 219
Rodolphe Poupardin is an academic researcher from Paracelsus Private Medical University of Salzburg. The author has contributed to research in topics: Stromal cell & Induced pluripotent stem cell. The author has an hindex of 4, co-authored 15 publications receiving 67 citations.
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CD8+ T-cells infiltrate Alzheimer's disease brains and regulate neuronal- and synapse-related gene expression in APP-PS1 transgenic mice.
Michael S. Unger,E Li,L Scharnagl,Rodolphe Poupardin,Barbara Altendorfer,Heike Mrowetz,Birgit Hutter-Paier,T M Weiger,Michael T. Heneka,Johannes Attems,Ludwig Aigner +10 more
TL;DR: CD8+ T-cells infiltrate the aged and AD brain and that brain CD8+T-cells might directly contribute to neuronal dysfunction in modulating synaptic plasticity as well as contribute to AD pathology.
Journal ArticleDOI
Adherence to minimal experimental requirements for defining extracellular vesicles and their functions.
TL;DR: This paper performed a systematic review using a text mining approach to assess adherence to the minimal information for studies of extracellular vesicles (MISEV) guidelines for assuring and improving EV research quality.
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Self-assembly of differentiated progenitor cells facilitates spheroid human skin organoid formation and planar skin regeneration.
Patricia Ebner-Peking,Linda Krisch,Martin Wolf,Sarah Hochmann,Anna Hoog,Balazs Vari,Katharina Muigg,Rodolphe Poupardin,Cornelia Scharler,Sabine Schmidhuber,Elisabeth Russe,Harald Stachelscheid,Achim Schneeberger,Katharina Schallmoser,Dirk Strunk +14 more
TL;DR: In this article, the authors demonstrated 3D self-assembly of adult and induced pluripotent stem cell (iPSC)-derived fibroblasts, keratinocytes and endothelial progenitors into both, planar human skin in vivo and a novel type of spheroid-shaped skin organoids in vitro, under the aegis of human platelet lysate.
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Microglia depletion diminishes key elements of the leukotriene pathway in the brain of Alzheimer’s Disease mice
Johanna Michael,Michael S. Unger,Rodolphe Poupardin,P. Schernthaner,Heike Mrowetz,Johannes Attems,Ludwig Aigner +6 more
TL;DR: Microglia are key in Leukotriene (LT) biosynthesis, and they regulate neuronal 5-Lipoxygenase (5-Lox) expression implying a yet unknown signaling mechanism between neurons and microglia.
Journal ArticleDOI
Heparin Differentially Impacts Gene Expression of Stromal Cells from Various Tissues
Sandra Laner-Plamberger,Michaela Oeller,Rodolphe Poupardin,Linda Krisch,Sarah Hochmann,Ravi C. Kalathur,Ravi C. Kalathur,Karin Pachler,Christina Kreutzer,Gerrit Erdmann,Eva Rohde,Dirk Strunk,Katharina Schallmoser +12 more
TL;DR: Hparin had no substantial effect on long-term proliferation and in vitro tri-lineage differentiation of stromal cells, indicating compatibility for clinically applied cell products.