S
Sandra Laner-Plamberger
Researcher at Paracelsus Private Medical University of Salzburg
Publications - 20
Citations - 1525
Sandra Laner-Plamberger is an academic researcher from Paracelsus Private Medical University of Salzburg. The author has contributed to research in topics: Medicine & Stromal cell. The author has an hindex of 9, co-authored 15 publications receiving 1099 citations.
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Journal ArticleDOI
Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper
Thomas Lener,Mario Gimona,Ludwig Aigner,Verena Börger,Edit I. Buzás,Giovanni Camussi,Nathalie Chaput,Devasis Chatterjee,Felipe A. Court,Hernando A. del Portillo,Lorraine O'Driscoll,Stefano Fais,Juan M. Falcón-Pérez,Ursula Felderhoff-Mueser,Lorenzo Fraile,Yong Song Gho,André Görgens,Ramesh C. Gupta,An Hendrix,Dirk M. Hermann,Andrew F. Hill,Fred H. Hochberg,Peter A. Horn,Dominique P.V. de Kleijn,Lambros Kordelas,Boris W. Kramer,Eva-Maria Krämer-Albers,Sandra Laner-Plamberger,Saara Laitinen,Tommaso Leonardi,Magdalena J. Lorenowicz,Sai Kiang Lim,Jan Lötvall,Casey A. Maguire,Antonio Marcilla,Irina Nazarenko,Takahiro Ochiya,Tushar Patel,Shona Pedersen,Gabriella Pocsfalvi,Stefano Pluchino,Peter J. Quesenberry,Ilona G. Reischl,Francisco J. Rivera,Ralf Sanzenbacher,Katharina Schallmoser,Ineke Slaper-Cortenbach,Dirk Strunk,Torsten Tonn,Pieter Vader,Pieter Vader,Bas W.M. van Balkom,Marca H. M. Wauben,Samir El Andaloussi,Samir El Andaloussi,Clotilde Théry,Eva Rohde,Bernd Giebel +57 more
TL;DR: In this paper, the authors summarize recent developments and the current knowledge of extracellular vesicles (EVs) and discuss safety and regulatory requirements that must be considered for pharmaceutical manufacturing and clinical application.
Journal ArticleDOI
Manufacturing of Human Extracellular Vesicle-Based Therapeutics for Clinical Use
TL;DR: The requirements for manufacturing, safety, and efficacy testing of EVs along their path from the laboratory to the patient are discussed and strategies for advancing mesenchymal stromal cell (MSC)-derived EV-based therapies are focused on.
Journal ArticleDOI
An In Vitro Potency Assay for Monitoring the Immunomodulatory Potential of Stromal Cell-Derived Extracellular Vesicles.
Karin Pachler,Nina Ketterl,Alexandre Desgeorges,Zsuzsanna A. Dunai,Sandra Laner-Plamberger,Doris Streif,Dirk Strunk,Eva Rohde,Mario Gimona +8 more
TL;DR: A dual in vitro immunomodulation potency assay is evaluated that reproducibly reports the inhibitory effect of MSCs on induced T-cell proliferation and the alloantigen-driven mixed leukocyte reaction of pooled peripheral blood mononuclear cells in a dose-dependent manner.
Journal ArticleDOI
International Forum on GMP-grade human platelet lysate for cell propagation: summary
Dirk Strunk,Miquel Lozano,Denese C. Marks,Yen Siew Loh,G. Gstraunthaler,H. Schennach,Eva Rohde,Sandra Laner-Plamberger,Michaela Öller,Johanna Nystedt,Ramin Lotfi,Markus Rojewski,Hubert Schrezenmeier,Karen Bieback,Richard Schäfer,Tamam Bakchoul,M. Waidmann,Sandra Mjoll Jonsdottir-Buch,H. Montazeri,Olafur E. Sigurjonsson,P. Iudicone,Daniela Fioravanti,Luca Pierelli,Martino Introna,C. Capelli,A. Falanga,Minoko Takanashi,O. Lόpez-Villar,Thierry Burnouf,Jo Anna Reems,Jan Pierce,Amber Preslar,Katharina Schallmoser +32 more
TL;DR: D. Strunk, M. Lozano, D. Marks, Y. Loh, G. Schennach, E. Rohde, S. Nystedt, R. Rojewski, H. Reems, J. Pierce, A. Preslar & K. Schallmoser
Journal ArticleDOI
Identification of new molecular targets for PET imaging of the microglial anti-inflammatory activation state.
Alessandro Villa,Barbara Klein,Bieneke Janssen,Jordi Pedragosa,Giovanna Pepe,Bastian Zinnhardt,Danielle J. Vugts,Paolo Gelosa,Luigi Sironi,Wissam Beaino,Annelaure Damont,Frédéric Dollé,Benoit Jego,Alexandra Winkeler,Dieter Ory,Olof Solin,Johnny Vercouillie,Uta Funke,Uta Funke,Sandra Laner-Plamberger,Linda V. Blomster,Palle Christophersen,Elisabetta Vegeto,Ludwig Aigner,Andreas H. Jacobs,Anna M. Planas,Adriana Maggi,Albert D. Windhorst +27 more
TL;DR: Evidence that P2RY12 expression increases in murine and human microglia following exposure to anti-inflammatory stimuli, and that its expression is modulated in the reparative phase of experimental and clinical stroke is provided.