R
Rodrigo A. de Souza
Researcher at Sao Paulo State University
Publications - 15
Citations - 248
Rodrigo A. de Souza is an academic researcher from Sao Paulo State University. The author has contributed to research in topics: Isonicotinamide & Broiler. The author has an hindex of 7, co-authored 15 publications receiving 207 citations.
Papers
More filters
Journal ArticleDOI
New drugs with antiprotozoal activity from marine algae: a review
Fábio Aurélio Esteves Torres,Thais Gaban Passalacqua,Angela Maria Arenas Velásquez,Rodrigo A. de Souza,Pio Colepicolo,Marcia A. S. Graminha +5 more
TL;DR: This current review describes the main substances biosynthesized by benthic marine algae with activity against Leishmania spp.
Journal ArticleDOI
Antimycobacterial and antitumor activities of palladium(II) complexes containing isonicotinamide (isn): X-ray structure of trans-[Pd(N3)2(isn)(2)].
Rodrigo A. de Souza,Alessandra Stevanato,O. Treu-Filho,Adelino Vieira de Godoy Netto,Antonio Eduardo Mauro,Eduardo E. Castellano,Iracilda Zeppone Carlos,Fernando Rogério Pavan,Clarice Queico Fujimura Leite +8 more
TL;DR: Among the complexes, compound 2 was found to be the most active with MIC of 35.89 μM, and single crystal X-ray diffraction determination showed that coordination geometry around Pd(II) is nearly square planar, with the ligands in a trans configuration.
Journal ArticleDOI
Experimental and theoretical study of the compound (Pd(dmba)(NCO)(imz))
O. Treu-Filho,José Ciríaco Pinheiro,Edson B. Costa,João E. V. Ferreira,Antonio Florêncio de Figueiredo,Rogério Toshiaki Kondo,Vicente Alexandre de Lucca Neto,Rodrigo A. de Souza,Alexandre de Oliveira Legendre,Antonio Eduardo Mauro +9 more
TL;DR: In this paper, a Gaussian basis set for the constituent atoms of the compound [Pd(dmba)(NCO)(imz)] was built and, after adequate supplementation with polarization and diffuse functions, they were used to study the molecule.
Journal ArticleDOI
Antiprotozoal Activity of the Cyclopalladated Complexes Against Leishmania amazonensis and Trypanosoma cruzi
Angela Maria Arenas Velásquez,Rodrigo A. de Souza,Thais Gaban Passalacqua,Aline Rimoldi Ribeiro,Mateus Scontri,Chung M. Chin,Leticia de Almeida,Mayara L. Del Cistia,João Aristeu da Rosa,Antonio Eduardo Mauro,Marcia A. S. Graminha +10 more
TL;DR: In this paper, the antiprotozoal properties of cyclopalladated compounds against leishmaniasis and trypanosoma brucei were described, which indicated that this compound presented higher selectivity for these parasites than the other tested compounds.
Journal ArticleDOI
Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B.
Angela Maria Arenas Velásquez,Willian C. Ribeiro,Vutey Venn,Silvia Castelli,Mariana Santoro de Camargo,Renata Pires Assis,Rodrigo A. de Souza,Aline Rimoldi Ribeiro,Thais Gaban Passalacqua,João Aristeu da Rosa,Amanda Martins Baviera,Antonio Eduardo Mauro,Alessandro Desideri,Elmo E. Almeida-Amaral,Marcia A. S. Graminha +14 more
TL;DR: In vivo assays using L. amazonensis-infected BALB/c showed an 80% reduction in parasite load compared to infected and nontreated animals, and CP2 did not show any side effects, and was able to inhibit Leishmania donovani topoisomerase 1B (Ldtopo1B), a potentially important target in this parasite.