Showing papers by "Roger G. Kathol published in 1986"
TL;DR: The number of anxiety symptoms paralleled the number of hyperthyroid symptoms whereas depressive symptoms did not, and the number with depression and anxiety was felt to be artificially inflated by the concurrent presence of somatic thyroid symptoms.
82 citations
TL;DR: Nine of 29 consecutively evaluated patients with hyperthyroidism in a general endocrine clinic were found according to DSM-III criteria to have major depressive disorder (organic affective disorder) while 23 of the 29 had symptoms of generalized anxiety.
73 citations
TL;DR: Pharmacologic intervention was attempted in three patients and was successful in one and the potential mechanisms by which these pharmacologic agents might alter thirst in patients with primary polydipsia are discussed.
Abstract: Psychiatric patients presenting with chronic psychogenic polydipsia are often difficult to treat with standard psychiatric interventions. Pharmacologic intervention was attempted in three patients and was successful in one. One patient had a significant and sustained reduction of water intake while on 160 mg of propranolol. One patient did not improve with either propranolol or captopril while a third patient showed no improvement of serum sodium with demeclocycline nor reduction of water intake with propranolol. The potential mechanisms by which these pharmacologic agents might alter thirst in patients with primary polydipsia are discussed.
13 citations
TL;DR: It is suggested that patients with a history of depression and DST nonsuppression have greater variability in cortisol excretion than a control population while in the compensated state.
Abstract: Seven male recovered depressive patients who were dexamethasone suppression test (DST) nonsuppressors while ill and eight male controls submitted an average of thirty-six 24-hr urine specimens for analysis during a 12-mo collection period. Recovered depressive patients had a significantly greater mean peak amplitude (mean distance from fitted regression line to the highest point on the peak) when compared to controls. Peak frequency (number of peaks per year) for recovered depressive patients for peaks greater than 30μg/g-cr was three times that found in the control population. The number of collections by each patient did not account for these differences. Only one of seven recovered depressives had a circasemiannual rhythm of Cortisol excretion while none demonstrated a seasonal rhythm. These findings suggest that patients with a history of depression and DST nonsuppression have greater variability in Cortisol excretion than a control population while in the compensated state.
8 citations
4 citations