R
Roger Lester
Researcher at University of Pittsburgh
Publications - 39
Citations - 2386
Roger Lester is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Intestinal absorption & Feminization (biology). The author has an hindex of 23, co-authored 39 publications receiving 2352 citations. Previous affiliations of Roger Lester include University of Texas Health Science Center at Houston & National Institutes of Health.
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Journal ArticleDOI
Gastrointestinal transit the effect of the menstrual cycle
Arnold Wald,Arnold Wald,David H. Van Thiel,David H. Van Thiel,Leah Hoechstetter,Leah Hoechstetter,Judith S. Gavaler,Judith S. Gavaler,Kimberly M. Egler,Kimberly M. Egler,Raymond Verm,Raymond Verm,Larry D. Scott,Larry D. Scott,Roger Lester,Roger Lester +15 more
TL;DR: Gastrointestinal transit time as well as serum estradiol and progesterone levels were measured in 15 normally menstruating women twice during their menstrual cycle, once in the follicular phase and onset of menses at the expected time documenting ovulatory cycles.
Journal ArticleDOI
Hypogonadism in alcoholic liver disease: evidence for a double defect.
David H. Van Thiel,David H. Van Thiel,Roger Lester,Roger Lester,Richard J. Sherins,Richard J. Sherins +5 more
TL;DR: No correlation between any specific biochemical assessment of the severity of liver disease and the degree of hormonal derangement was observed, but mean plasma testosterone levels were lower than normal.
Journal ArticleDOI
Alcohol-induced testicular atrophy. An experimental model for hypogonadism occurring in chronic alcoholic men.
David H. Van Thiel,David H. Van Thiel,Judith S. Gavaler,Judith S. Gavaler,Roger Lester,Roger Lester,M. David Goodman,M. David Goodman +7 more
TL;DR: In this article, an animal model was developed to examine perturbation in gonadal function that occurs in man as a consequence of chronic ethanol ingestion and confirms previous data which suggest that ethanol is a primary testicular toxin.
Journal ArticleDOI
Effect of pregnancy on gastrointestinal transit.
Arnold Wald,Arnold Wald,David H. Van Thiel,David H. Van Thiel,Leah Hoechstetter,Leah Hoechstetter,Judith S. Gavaler,Judith S. Gavaler,Kimberly M. Egler,Kimberly M. Egler,Ray Verm,Ray Verm,Larry D. Scott,Larry D. Scott,Roger Lester,Roger Lester +15 more
TL;DR: This study supports previous findings which suggest that increasing levels of progesterone and estradiol affect gastrointestinal function and therefore may contribute to gastrointestinal symptoms that often occur in pregnant women.
Journal ArticleDOI
Ethanol inhibition of vitamin A metabolism in the testes: possible mechanism for sterility in alcoholics.
TL;DR: A possible biochemnical mechanism for the sterility of chronic alcoholics is identified through inhibited oxidation of retinol by testicular homogenates containing alcohol dehydrogenase.