Showing papers in "Gastroenterology in 1974"

TL;DR: The newly discovered epithelial cells contain multiple vesicles that suggest a transport function, possibly for luminal antigenic material or for secretory immunoglobulin, in human intestinal mucosal cell type M cells.

TL;DR: It is demonstrated that the physiological responses related to food ingestion are important in maintaining small intestinal mass, disaccharidase activity, and the proximal-distal gradient.

TL;DR: No correlation between any specific biochemical assessment of the severity of liver disease and the degree of hormonal derangement was observed, but mean plasma testosterone levels were lower than normal.

TL;DR: Two important intestinal diseases of childhood underscore the notion that it is the molecular structure of macromolecules that is critical to the pathogenesis of some immunologically mediated gastrointestinal diseases.

TL;DR: In dogs with Heidenhain pouches and gastric fistulae of the main stomach, metiamide, a histamine antagonist of the H2-blocking variety, in a dose of 12 µmoles kg-1 intravenously, inhibited gastric acid secretion during stimulation by histamine, pentagastrin, 2-deoxyglucose, and food (liver extract).

TL;DR: No substantial differences were observed with regard to bleeding, encephalopathy, or hepatic function, although the side-side shunt provided better control of ascites, and published data do not exclude the possibility that a therapeutic portacaval shunt may allow longer survival for the patient with a single major variceal hemorrhage.

TL;DR: Intestinal oxalate absorption as reflected by renalOxalate excretion was studied in normal subjects, in patients with an ileostomy who had total colectomy, and in patients who had ileal resection for regional enteritis.

TL;DR: A specific radioimmunoassay for gastric inhibitory polypeptide has been developed using guinea pig antisera raised to porcine gastric inhibitsory polyPEptide and Reproducibility of determinations in different assays was demonstrated.

TL;DR: Acute intragastric administration of ethanol in concentrations similar to those of common alcoholic beverages produced hemorrhagic erosions of the small intestinal villi in rats, which were most obvious proximally and were concentration-dependent.

TL;DR: This study suggests that a primary defect in the local secretory immunoglobulin system cannot explain the development of ulcerative colitis, and suggests a pronounced local IgG immunocyte response is associated with the pathogenesis of this disease.

TL;DR: Junal, ileal, and colonic water and electrolyte transport was studied in Shigella flexneri 2a-infected monkeys to find out why shigellosis is both a small and large intestinal disease.

TL;DR: The ability of the mature small intestine to absorb intact protein was studied in adult rats prepared with duodenal cannulas, mesenteric lymph fistulae, and portal vein cannulas to provide additional evidence for the concept that intact protein can traverse the mature intestinal epithelium under physiologic conditions.

TL;DR: It is suggested that increased cholesterol saturation of bile during administration of a natural estrogen with progestin to cholecystectomized patients relects an increased propensity to cholesterol formation.

TL;DR: The pathogenesis of stress ulceration remains unexplained, and preliminary experiments on rats found that nonlethal hemorrhagic shock induced by removing a volume of blood equivalent to 2.0% of body weight caused severe gastric epithelial necrosis within 15 min and gross erosions within 45 min.

TL;DR: It was found that the reflux lesions were distributed randomly over the distal 8 cm of esophagus, suggesting that precise manometric localization of biopsy site is not necessary and that multiple biopsies are helpful.

TL;DR: The results suggest that the increase of the CCl4 hepatotoxicity in chronic ethanol-fed rats is due to an enhanced microsomal activation and biotransformation of CCl 4.

TL;DR: Although some patients improved dramatically on azathioprine, others improved during the placebo period, and this study does not provide evidence to support the effectiveness of azATHioprine in the treatment of Crohn's disease.

TL;DR: The size of the total bile acid pool in cholecystectomized patients correlated highly with thesize of the pool of secondary bile acids, suggesting that its apparent return to a normal size in these patients after choleCystectomy could be explained in part by the increased input of secondarybile acids from the intestine.

TL;DR: Four methods for detecting Giardia lamblia, namely examinations of stools, duodenal aspirates, intestinal biopsies, and impression smears of intestinal mucosa, were evaluated prospectively in 21 Malaysian children with acute or chronic diarrheal disease or with malabsorption.

TL;DR: It is suggested that oxalate transport is a nonenergy-dependent, nonsaturable process and changes in oxalates solubility may, in part, explain the increasedOxalate absorption of ileal disease.

TL;DR: An assay was developed which measured in vitro DNA synthesis in small pieces of tissue and demonstrated that 250 μg per kg of pentagastrin was optimal for these effects on DNA synthesis.

TL;DR: The neuropsychiatric syndrome seen secondary to liver disease is called hepatic coma or encephalopathy, the latter term describing more comprehensively the wide neurological spectrum of this disorder.

TL;DR: Marked hypergastrinemia characterized by high fasting levels and a prompt sharp response to a standard test meal was observed in a group of 4 patients with short bowel syndrome, but not in a patient with jejunoileal bypass.

TL;DR: It is possible that arsenic is an etiological factor in the production of noncirrhotic portal hypertension in some patients, perhaps because of damage to the intrahepatic portal veins.

TL;DR: Patients with dermatitis herpetiformis and morphologically normal small intestinal mucosa may have a latent form of celiac sprue, and Moderately abnormal and severe "flat" mucosal lesions were induced in both patients with DH and normal volunteer.

TL;DR: A review of the culture reports and clinical records of all Baltimore Cancer Research Center patients undergoing endoscopy with a flexible fiberoptic esophagoscope revealed widespread contamination by enteric organisms, including Pseudomonas aeruginosa, and routine handling of the instrument ignored aseptic technique.