R
Roland J. Levinsky
Researcher at University of London
Publications - 107
Citations - 7570
Roland J. Levinsky is an academic researcher from University of London. The author has contributed to research in topics: X-linked agammaglobulinemia & Gene. The author has an hindex of 34, co-authored 106 publications receiving 7391 citations. Previous affiliations of Roland J. Levinsky include University College London & UCL Institute of Child Health.
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Journal ArticleDOI
CD15 antibodies increase neutrophil adhesion to endothelium by an LFA-1-dependent mechanism.
TL;DR: It is demonstrated that pre‐incubation of neutrophils with a CD15 antibody increases neutrophil adherence to endothelium by a neutrophIL‐dependent mechanism.
Journal ArticleDOI
Mutation analysis in Bruton's tyrosine kinase, the X-linked agammaglobulinaemia gene, including identification of an insertional hotspot
Hubert B. Gaspar,Linda A. D. Bradley,F. Katz,Ruth C. Lovering,Chaim M. Roifman,Gareth J. Morgan,Roland J. Levinsky,Christine Kinnon +7 more
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Superoxide production by normal and chronic granulomatous disease (CGD) patient-derived EBV-transformed B cell lines measured by chemiluminescence-based assays.
TL;DR: Assays for products of the neutrophil respiratory burst in normal EBV-transformed B cell lines stimulated with agonists of protein kinase C were compared, finding the most sensitive were the lucigenin- and luminol-based chemiluminescence assays for O2- and H2O2 respectively.
Journal Article
Expression of the X-linked agammaglobulinemia gene, btk in B-cell acute lymphoblastic leukemia.
F. Katz,Ruth C. Lovering,Linda A. D. Bradley,Kevin Rigley,Dennis Brown,F. Cotter,J. M. Chessells,Roland J. Levinsky,Christine Kinnon +8 more
TL;DR: Data suggest that btk does not appear to play a critical role in childhood B-cell leukemias, and specific primers covering the coding region of the btk cDNA for mutations were screened using single strand conformation polymorphism (SSCP).
Journal ArticleDOI
Prenatal diagnosis and carrier detection in primary immunodeficiency disorders.
Yu-Lung Lau,Roland J. Levinsky +1 more
TL;DR: The individual forms of inherited immunodeficiency diseases are rare and the true incidence in the United Kingdom is not known, but with increasing awareness among paediatricians and with better laboratory facilities more of these children will be identified.