Ron Harris

TL;DR: The clinical features, age at onset of symptoms and survival of 150 patients with type 2 neurofibromatosis were studied and there are marked inter-family differences in disease severity and tumour susceptibility.

TL;DR: In this article, a clinical and genetic study of type 2 neurofibromatosis (NF2) has been carried out in the United Kingdom and the results show that there are two types of NF2, one with later onset and bilateral vestibular schwannomas as the only usual feature and the other with earlier onset and multiple other tumours.

TL;DR: Data are presented which suggest that there are two types of NF2, one with later onset and bilateral bilateral schwannomas as the only usual feature, and the other with earlier onset and multiple other tumours.

TL;DR: A clinical study of patients on the North West Regional Genetic Register with neurofibromatosis type 1 (NF1) identified 523 affected cases from 304 families and actuarial analyses were carried out for both optic glioma and malignant nerve sheath tumours.

TL;DR: In 97 cases studied personally by the authors, skin and eye examination were found to be useful to detect early signs of the condition and a screening protocol is proposed and the effect of disease heterogeneity on management is discussed.