R
Ron Orbach
Researcher at Hebrew University of Jerusalem
Publications - 34
Citations - 3137
Ron Orbach is an academic researcher from Hebrew University of Jerusalem. The author has contributed to research in topics: Self-healing hydrogels & Deoxyribozyme. The author has an hindex of 26, co-authored 33 publications receiving 2723 citations. Previous affiliations of Ron Orbach include Tel Aviv University & Yale University.
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Journal ArticleDOI
Amplified Analysis of DNA by the Autonomous Assembly of Polymers Consisting of DNAzyme Wires
TL;DR: The amplification mixture composed of the two hairpins can be implemented as a versatile sensing platform for analyzing any gene in the presence of the appropriate hairpin probe.
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Amplified detection of DNA through the enzyme-free autonomous assembly of hemin/G-quadruplex DNAzyme nanowires.
TL;DR: An enzyme-free amplified detection platform is described using the horseradish peroxidase (HRP)-mimicking DNAzyme as an amplifying label and by coaddition of a "helper" hairpin structure any DNA sequence may be analyzed by the system.
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pH-stimulated DNA hydrogels exhibiting shape-memory properties.
Weiwei Guo,Chun-Hua Lu,Ron Orbach,Fuan Wang,Xiu-Juan Qi,Xiu-Juan Qi,Alessandro Cecconello,Dror Seliktar,Itamar Willner +8 more
TL;DR: Nucleic acid-functionalized polyacrylamide chains that are cooperatively cross-linked by i-motif and nucleic acid duplex units yield, at pH 5.0, DNA hydrogels exhibiting shape-memory properties, allowing the regeneration of the hydrogel shape at pH5.0.
Journal ArticleDOI
Self-assembled Fmoc-peptides as a platform for the formation of nanostructures and hydrogels.
TL;DR: This work describes the self-assembly of these Fmoc-peptides into various structures and characterize their distinctive molecular and physical properties, which offers new opportunities for developing cell-adhesive biomedical hydrogel scaffolds, as well as for establishing strategies to modify surfaces with bioactive materials.
Journal ArticleDOI
The rheological and structural properties of Fmoc-peptide-based hydrogels: the effect of aromatic molecular architecture on self-assembly and physical characteristics.
Ron Orbach,Iris Mironi-Harpaz,Lihi Adler-Abramovich,Estelle Mossou,Edward P. Mitchell,V. Trevor Forsyth,Ehud Gazit,Dror Seliktar +7 more
TL;DR: The structural and thermal properties of Fmoc-peptide-based hydrogels for medical applications are described and the role of interactions between aromatic moieties in the self-assembly process and on the physical and structural properties of the hydrogel is studied.