R
Ronald A. Hill
Researcher at Cosmetic Ingredient Review
Publications - 191
Citations - 3277
Ronald A. Hill is an academic researcher from Cosmetic Ingredient Review. The author has contributed to research in topics: Cosmetics & Medicine. The author has an hindex of 27, co-authored 167 publications receiving 2521 citations. Previous affiliations of Ronald A. Hill include University of Louisiana at Monroe & Ohio State University.
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Journal ArticleDOI
The effect of PAMAM dendrimer generation size and surface functional group on the aqueous solubility of nifedipine
TL;DR: The aim of this study was to investigate the effect of low generation (G0-G3) ethylenediamine (EDA) core poly(amidoamine) (PAMAM) dendrimers on the aqueous solubility of nifedipine.
Journal ArticleDOI
Comparison of the aqueous solubilization of practically insoluble niclosamide by polyamidoamine (PAMAM) dendrimers and cyclodextrins
TL;DR: Higher equilibrium stability constants and complexation efficiency showed that the PAMAM dendrimers formed stronger more stable complexes than the CDs, and the strong interaction between the amine surface functional groups and the niclosamide molecule complexes caused a decrease in dissolution rate compared to the CDs.
Book ChapterDOI
Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance.
Yong-Yu Liu,Ronald A. Hill,Y Li +2 more
TL;DR: Mechanistic studies indicate that uncoupling ceramide glycosylation can modulate gene expression, decreasing MDR1 through the cSrc/β-catenin pathway and restoring p53 expression via RNA splicing and provide novel therapeutic approaches for targeting refractory tumors.
Journal ArticleDOI
Enhanced brain amyloid-β clearance by rifampicin and caffeine as a possible protective mechanism against Alzheimer's disease.
TL;DR: It is hypothesized that enhanced amyloid-β clearance from the brain across the blood-brain barrier (BBB) of wild-type mice treated with rifampicin or caffeine is caused by both drugs potential to upregulate low-density lipoprotein receptor related protein-1 (LRP1) and/or P-glycoprotein (P-gp) at the BBB.
Journal ArticleDOI
Saturation toxicokinetics of thioacetamide: role in initiation of liver injury.
TL;DR: With increasing doses, the apparent elimination half-lives of TA and TASO increased linearly, indicating that TA bioactivation exhibits saturation kinetics, and indicates saturation of CYP2E1 at the first and second steps of TA bio activation.