R
Ronald W. Ratcliffe
Researcher at Merck & Co.
Publications - 109
Citations - 1718
Ronald W. Ratcliffe is an academic researcher from Merck & Co.. The author has contributed to research in topics: Alkyl & Thienamycin. The author has an hindex of 22, co-authored 109 publications receiving 1697 citations. Previous affiliations of Ronald W. Ratcliffe include Merial.
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A stereocontrolled synthesis of (+)-thienamycin
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A novel synthesis of the carbapen-2-em ring system
TL;DR: In this article, a new synthesis of the carbapenem ring system, as found in thienamycin and related natural products, has been developed, which involves a highly efficient carbene insertion reaction which produces the bicyclic ring system by forming the N3 bond.
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Total synthesis of beta-lactam antibiotics. IV. Epimerization of 6(7)-aminopenicillins and -cephalosporins from alpha to beta.
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