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A stereocontrolled synthesis of (+)-thienamycin
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This article is published in Journal of the American Chemical Society.The article was published on 1980-09-01. It has received 340 citations till now. The article focuses on the topics: Thienamycin.read more
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Click Chemistry: Diverse Chemical Function from a Few Good Reactions.
TL;DR: In this paper, a set of powerful, highly reliable, and selective reactions for the rapid synthesis of useful new compounds and combinatorial libraries through heteroatom links (C-X-C), an approach called click chemistry is defined, enabled, and constrained by a handful of nearly perfect "springloaded" reactions.
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Click-Chemie: diverse chemische Funktionalität mit einer Handvoll guter Reaktionen
TL;DR: In this paper, the authors show how in der Natur am haufigsten vorkommenden Verbindungen, so fallt auf, dass the Bildung von Kohlenstoff-Heteroatom-Bindungen gegenuber der von KHO-Kohlenstoffs-KHO-Bindingsen deutlich bevorzugt is, and das Medium naturlicher Reaktionen zumeist Wasser ist.
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Carbapenems: Past, Present, and Future
Krisztina M. Papp-Wallace,Andrea Endimiani,Andrea Endimiani,Andrea Endimiani,Magdalena A. Taracila,Robert A. Bonomo +5 more
TL;DR: The current “state of the art” of carbapenem antibiotics and their role in the antimicrobial armamentarium are summarized and the medicinal chemist is urged to continue development of these versatile and potent compounds.