R
Rongqi Wang
Researcher at Cardiovascular Institute of the South
Publications - 10
Citations - 1004
Rongqi Wang is an academic researcher from Cardiovascular Institute of the South. The author has contributed to research in topics: Apoptosis & Angiotensin II. The author has an hindex of 9, co-authored 9 publications receiving 968 citations. Previous affiliations of Rongqi Wang include Northwestern University.
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Journal ArticleDOI
Abrogation of bleomycin-induced epithelial apoptosis and lung fibrosis by captopril or by a caspase inhibitor.
TL;DR: The data suggest that the efficacy of captopril to inhibit experimental lung fibrogenesis is related to inhibition of apoptosis and the antifibrotic potential of a caspase inhibitor is demonstrated.
Journal ArticleDOI
Angiotensin II induces apoptosis in human and rat alveolar epithelial cells
Rongqi Wang,Alex Zagariya,Olivia Ibarra-Sunga,Claudia Gidea,Edmund Ang,Sonali Deshmukh,Gaurav Chaudhary,John Baraboutis,Gerasimos Filippatos,Bruce D. Uhal +9 more
TL;DR: The presence of a functional ANG II-dependent pathway for apoptosis in human and rat AECs is demonstrated and a role for the ANG II receptor and ACE in the induction of AEC apoptosis is suggested in vivo.
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Fas-induced apoptosis of alveolar epithelial cells requires ANG II generation and receptor interaction.
TL;DR: The data indicate that the induction of AEC apoptosis by Fas requires a functional renin-angiotensin system in the target cell and suggest that therapeutic control of A EC apoptosis is feasible through pharmacological manipulation of the local ren in-angiotsin system.
Journal ArticleDOI
Apoptosis of lung epithelial cells in response to TNF-alpha requires angiotensin II generation de novo.
Rongqi Wang,Golam Alam,Alex Zagariya,Claudia Gidea,Hugo Pinillos,Omosalewa Lalude,Gaurav Choudhary,Devlet Oezatalay,Bruce D. Uhal +8 more
TL;DR: Data indicate that the induction of A EC apoptosis by TNF‐α requires a functional renin/angiotensin system (RAS) in the target cell and suggest that therapeutic control of AEC apoptosis in response to TNF-α is feasible through pharmacologic manipulation of the local RAS.
Journal ArticleDOI
Angiotensin receptor subtype AT1 mediates alveolar epithelial cell apoptosis in response to ANG II
TL;DR: Data indicate that AEC apoptosis in response to ANG II is mediated by receptor subtype AT(1), despite the expression of mRNAs for both AT( 1) and AT(2).