R
Rongrong Chen
Researcher at Medical Park
Publications - 16
Citations - 73
Rongrong Chen is an academic researcher from Medical Park. The author has contributed to research in topics: Lung cancer & Crizotinib. The author has an hindex of 3, co-authored 16 publications receiving 50 citations.
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Journal ArticleDOI
Next-generation sequencing based mutation profiling reveals heterogeneity of clinical response and resistance to osimertinib.
Jun Zhao,Gen Lin,Minglei Zhuo,Zaiwen Fan,Liyun Miao,Likun Chen,Aiping Zeng,Rong Yin,Yangming Ou,Zhihui Shi,Jie Yin,Wen Gao,Jianhua Chen,Xiangdong Zhou,Yong Zeng,Xiang Liu,Huamin Xu,Rongrong Chen,Xuefeng Xia,David P. Carbone +19 more
TL;DR: Heterogeneity of resistance to osimertinib was not only manifested by inter-individual differences, but also embodied in its intra-individual diversity.
Journal ArticleDOI
Next generation sequencing reveals a novel ALK G1128A mutation resistant to crizotinib in an ALK-Rearranged NSCLC patient
TL;DR: This case further illustrates the importance of comprehensive genomic profiling of resistant tumors for tailoring treatment decisions after disease progression on crizotinib in ALK + NSCLC in the era of rapidly developing new-generation ALK inhibitors and other therapeutic strategies.
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Identification of the BRAF V600E mutation in a patient with sclerosing pneumocytoma: A case report.
Guanming Jiang,Min Zhang,Qinquan Tan,Shunhuan Lin,Yihong Zeng,Chun Liu,Rongrong Chen,Jianping Zhou +7 more
TL;DR: This is the first case report of a BRAF V600E mutation in a patient with SP, which extends the understanding of the pathogenesis of SP, and suggests the need for future testing of BRAFV600E in this rare tumor type.
Journal ArticleDOI
EGFR extracellular domain mutation in patients with lung cancer.
Renhua Guo,Dejian Gu,Jun Zhao,Lingjun Zhu,Mingjiu Chen,Shuoyan Liu,Bo Tang,Rongrong Chen,Xuefeng Xia +8 more
TL;DR: This data indicates that EGFR EC domain mutations in the EGFR extracellular (EC) domain are associated with atypical granuloma recurrence in glioblastomas and this data points to the need for further research into these mutations to determine their role in lung cancer.
Journal ArticleDOI
A multicenter real-world study of tumor-derived DNA from pleural effusion supernatant in genomic profiling of advanced lung cancer.
TL;DR: Pleural effusion is commonly observed in advanced lung cancer and molecular profiling of PE represents a minimally invasive approach of detecting tumorigenicity in these patients.