Rongxiang Chen

TL;DR: The Cu-catalyzed three-component reaction between quinolines, diazo compounds, and alkenes has been established for direct construction of indolizine derivatives via quinolinium ylides.

TL;DR: This radical-carbene coupling reaction (RCC reaction) offers a novel approach for the preparation of various isoxazolines, which features the construction of C-C, C-O, and C═N bonds in a one-pot process.

TL;DR: The experimental studies and DFT calculations suggest that the reaction starts with the generation of the key intermediate nitrile oxides, followed by a [3 + 2] cycloaddition reaction of β-keto esters to give the final isoxazole products.

TL;DR: In this article , a TBAI-catalyzed S-H and N-H insertion reaction of α-diazoesters with thiophenols and aromatic amines under metal-free conditions has been described, furnishing a straightforward and general platform for the synthesis of various thioethers and 2-amino-2-oxoacetates.

TL;DR: The additive-free 1,3-dipolar cycloaddition reaction of isatin-derived azomethine ylides with α-cyano-α,β-unsaturated compounds was developed, which enabled diversity-oriented synthesis of a series of novel and structurally complex 3,3'-pyrrolidinyl-spirooxindoles derivatives containing four contiguous and two quaternary stereogenic centers in high yields and excellent diastereoselectivities as mentioned in this paper .