R
Rowena A. Bull
Researcher at University of New South Wales
Publications - 123
Citations - 4330
Rowena A. Bull is an academic researcher from University of New South Wales. The author has contributed to research in topics: Medicine & Hepatitis C virus. The author has an hindex of 27, co-authored 97 publications receiving 3337 citations. Previous affiliations of Rowena A. Bull include Kirby Institute.
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Journal ArticleDOI
Emergence of a New Norovirus Genotype II.4 Variant Associated with Global Outbreaks of Gastroenteritis
TL;DR: A nested reverse transcriptase PCR (nRT-PCR) that was designed to amplify the highly conserved 3′ end of the polymerase region and the 5′End of the capsid gene of NoV genogroup II (GII) was validated with strains isolated from sporadic and outbreak cases between 1997 and 2004 in Australia.
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Rapid evolution of pandemic noroviruses of the GII.4 lineage.
TL;DR: The hypothesis that the ability of the virus to generate genetic diversity is vital for viral fitness is supported, as it is shown that GII.4 viruses have both a higher frequency in the host population and greater epidemiological fitness.
Journal ArticleDOI
Norovirus recombination in ORF1/ORF2 overlap.
Rowena A. Bull,Grant S. Hansman,Leighton E. Clancy,Mark M. Tanaka,William D. Rawlinson,Peter A. White +5 more
TL;DR: Evidence is provided to support the theory of the role of subgenomic RNA promoters as recombination hotspots and a simple mechanism of how recombination might occur in NoV is described.
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Sequential bottlenecks drive viral evolution in early acute Hepatitis C virus infection
Rowena A. Bull,Fabio Luciani,Kerensa McElroy,Silvana Gaudieri,Son T. Pham,Abha Chopra,Barbara Cameron,Lisa Maher,Gregory J. Dore,Peter A. White,Andrew R. Lloyd +10 more
TL;DR: These results provide the first detailed analysis of early within-host evolution of HCV, indicating strong selective forces limit viral evolution in the acute phase of infection.
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Evolution of the SARS‐CoV‐2 omicron variants BA.1 to BA.5: Implications for immune escape and transmission
TL;DR: The theories that have been proposed on the evolution of Omicron including zoonotic spillage, infection in immunocompromised individuals and cryptic spread in the community without being diagnosed are examined.