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Rowland N. Otchwemah
Researcher at University for Development Studies
Publications - 26
Citations - 1712
Rowland N. Otchwemah is an academic researcher from University for Development Studies. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 20, co-authored 26 publications receiving 1635 citations. Previous affiliations of Rowland N. Otchwemah include Philippine Institute for Development Studies.
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Journal ArticleDOI
Toll-like receptor (TLR) polymorphisms in African children: Common TLR-4 variants predispose to severe malaria
Frank P. Mockenhaupt,Jakob P. Cramer,Jakob P. Cramer,Lutz Hamann,Miriam Stegemann,Jana Eckert,Na Ri Oh,Rowland N. Otchwemah,Ekkehart Dietz,Stephan Ehrhardt,Stephan Ehrhardt,Nicolas W. J. Schröder,Nicolas W. J. Schröder,Ulrich Bienzle,Ralf R. Schumann +14 more
TL;DR: TLR4-mediated responses to malaria in vivo and TLR-4 polymorphisms to be associated with disease manifestation are suggested, however some gray areas also suggest the scope for further improvements.
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Malaria, anemia, and malnutrition in african children--defining intervention priorities.
Stephan Ehrhardt,Gerd D. Burchard,Carsten Mantel,Jakob P. Cramer,Sarah Kaiser,Martina Kubo,Rowland N. Otchwemah,Ulrich Bienzle,Frank P. Mockenhaupt +8 more
TL;DR: Malnutrition is a fundamental factor contributing to malaria-associated morbidity and anemia, even if the latter exhibits multifactorial patterns, and the data demonstrate that malaria-control programs alone may not have the desired impact on childhood morbidity on a large scale without concomitant nutrition programs.
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Manifestation and outcome of severe malaria in children in northern ghana
Frank P. Mockenhaupt,Stephan Ehrhardt,Jana Burkhardt,Samuel Y. Bosomtwe,Stephen Laryea,Sylvester D. Anemana,Rowland N. Otchwemah,Jakob P. Cramer,Ekkehart Dietz,Sabine Gellert,Ulrich Bienzle +10 more
TL;DR: In hospitalized children with severe malaria in northern Ghana, severe anemia is the leading manifestation, but itself does not contribute to mortality, while in this region, malnutrition and circulatory collapse were important predictors of fatal malaria.
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α+-thalassemia protects African children from severe malaria
Frank P. Mockenhaupt,Stephan Ehrhardt,Sabine Gellert,Rowland N. Otchwemah,Ekkehart Dietz,Sylvester D. Anemana,Ulrich Bienzle +6 more
TL;DR: Protection against severe malaria was found to be pronounced comparing severe malaria patients with parasitemic controls and to wane with age, providing evidence for natural selection of α+-thalassemia in Africa due to protection from severe malaria.
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Acute childhood diarrhoea in northern Ghana: epidemiological, clinical and microbiological characteristics
Klaus Reither,Klaus Reither,Ralf Ignatius,Thomas Weitzel,Andrew Seidu-Korkor,Louis Anyidoho,Eiman Saad,Andrea Djie-Maletz,Peter Ziniel,Felicia Amoo-Sakyi,Francis Danikuu,Stephen Danour,Rowland N. Otchwemah,Eckart Schreier,Ulrich Bienzle,Klaus Stark,Frank P. Mockenhaupt +16 more
TL;DR: Rotavirus-infection is the predominant cause of acute childhood diarrhoea in urban northern Ghana and the abundance of putative enteropathogens among controls may indicate prolonged excretion or limited pathogenicity.