R
Roy D. Mugerwa
Researcher at Makerere University
Publications - 119
Citations - 9103
Roy D. Mugerwa is an academic researcher from Makerere University. The author has contributed to research in topics: Tuberculosis & Population. The author has an hindex of 50, co-authored 119 publications receiving 8759 citations. Previous affiliations of Roy D. Mugerwa include University of Medicine and Dentistry of New Jersey & College of Health Sciences, Bahrain.
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Journal ArticleDOI
Rapid Detection of Mycobacterium tuberculosis and Rifampin Resistance by Use of On-Demand, Near-Patient Technology
Danica Helb,Martin Jones,Elizabeth Story,Catharina Boehme,Ellen Wallace,Ken Ho,JoAnn Kop,Michelle R. Owens,Richard Rodgers,Padmapriya P. Banada,Hassan Safi,Robert Blakemore,N. T. Ngoc Lan,Edward C. Jones-López,Michael H. Levi,Michele Burday,Irene Ayakaka,Roy D. Mugerwa,Bill McMillan,Emily S. Winn-Deen,Lee A. Christel,Peter Dailey,Mark D. Perkins,David Persing,David Alland +24 more
TL;DR: The first analysis of the Cepheid Gene Xpert System's MTB/RIF assay is developed and performed, an integrated hands-free sputum-processing and real-time PCR system with rapid on-demand, near-patient technology, to simultaneously detect M. tuberculosis and rifampin resistance.
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Slim disease: a new disease in Uganda and its association with HTLV-III infection.
David Serwadda,Nelson K. Sewankambo,J.W. Carswell,A.C. Bayley,Richard S. Tedder,Robin A. Weiss,Roy D. Mugerwa,A. Lwegaba,G.B. Kirya,R.G. Downing,S.A. Clayden,Angus G. Dalgleish +11 more
TL;DR: The site and timing of the first reported cases suggest that the disease arose in Tanzania, and there is no clear evidence to implicate other possible means of transmission, such as by insect vectors or re-used injection needles.
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A Trial of Three Regimens to Prevent Tuberculosis in Ugandan Adults Infected with the Human Immunodeficiency Virus
Christopher C. Whalen,John L. Johnson,Alphonse Okwera,David L. Hom,R. Huebner,Peter Mugyenyi,Roy D. Mugerwa,Jerrold J. Ellner +7 more
TL;DR: A six-month course of isoniazid confers short-term protection against tuberculosis among PPD-positive, HIV-infected adults and multidrug regimens with isoniaZid and rifampin taken for three months also reduce the risk of tuberculosis.
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Depressed T-Cell Interferon-γ Responses in Pulmonary Tuberculosis: Analysis of Underlying Mechanisms and Modulation with Therapy
Christina S. Hirsch,Zahra Toossi,Catherine Othieno,John L. Johnson,S. K. Schwander,Steven S. Robertson,Robert S. Wallis,K. Edmonds,Alphonse Okwera,Roy D. Mugerwa,Pierre Peters,Jerrold J. Ellner +11 more
TL;DR: The data indicate that the immunosuppression of TB is not only immediate and apparently dependent (at least in part) on Immunosuppressive cytokines early during the course of Mycobacterium TB infection but is also long lasting, presumably relating to a primary abnormality in T-cell function.
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Multiple validated measures of adherence indicate high levels of adherence to generic HIV antiretroviral therapy in a resource-limited setting.
Jessica H. Oyugi,Jayne Byakika-Tusiime,Edwin D. Charlebois,Cissy Kityo,Roy D. Mugerwa,Peter Mugyenyi,David R. Bangsberg +6 more
TL;DR: The relative ease of administration of the 30-day visual analog scale suggests that this may be the preferred method to assess adherence in resource-poor settings.