R
Ruediger B Mueller
Researcher at Kantonsspital St. Gallen
Publications - 41
Citations - 966
Ruediger B Mueller is an academic researcher from Kantonsspital St. Gallen. The author has contributed to research in topics: Rheumatoid arthritis & Internal medicine. The author has an hindex of 14, co-authored 38 publications receiving 833 citations. Previous affiliations of Ruediger B Mueller include University of St. Gallen & University of Erlangen-Nuremberg.
Papers
More filters
Journal ArticleDOI
Altered skeletal expression of sclerostin and its link to radiographic progression in ankylosing spondylitis.
Heiner Appel,G. Ruiz-Heiland,Joachim Listing,Jochen Zwerina,Martin Herrmann,Ruediger B Mueller,Hildrun Haibel,Xenofon Baraliakos,Axel Hempfing,Martin Rudwaleit,Joachim Sieper,Georg Schett +11 more
TL;DR: Sclerostin expression is impaired in patients with AS, suggesting a specific alteration of osteocyte function in this disease, and a low serum level in the setting of AS is linked to increased structural damage, emphasizing the role of sclerost in the suppression of bone formation.
Journal ArticleDOI
Treatment with Biologicals in Rheumatoid Arthritis: An Overview
Philipp Rein,Ruediger B Mueller +1 more
TL;DR: The present review focuses on bDMARDs and tsDMARDS regarding similarities and possible drug-specific advantages in the treatment of RA and compounds not yet approved in RA and biosimilars are discussed.
Journal ArticleDOI
The Role of Annexin A5 in the Modulation of the Immune Response Against Dying and Dead Cells
Luis E. Muñoz,Benjamin Frey,Friederike Pausch,Wolfgang Baum,Ruediger B Mueller,Bent Brachvogel,Ernst Pöschl,Franz Rödel,Klaus von der Mark,Martin Herrmann,Udo S. Gaipl +10 more
TL;DR: The mechanism of how the immunogenicity of apoptotic cells can be restored by blocking their PS-dependent clearance is outlined in detail and the role of annexin A5 as important adjuvant for apoptotic cell-based tumour vaccines is discussed.
Journal ArticleDOI
Attraction of phagocytes by apoptotic cells is mediated by lysophosphatidylcholine.
TL;DR: Lysophosphatidylcholine, exerting this bivalent function, leads to a sufficient clearance of apoptotic cell as a “keep calm” mechanism to prevent activation of the immune system by secondary necrosis.
Journal ArticleDOI
Circulating chromogranin A reveals extra-articular involvement in patients with rheumatoid arthritis and curbs TNF-α-elicited endothelial activation
Gabriele Di Comite,Carlo Maria Rossi,Alessandro Marinosci,Karine Lolmede,Elena Baldissera,Patrizia Aiello,Ruediger B Mueller,Martin Herrmann,Reinhard E. Voll,Patrizia Rovere-Querini,Maria Grazia Sabbadini,Angelo Corti,Angelo A. Manfredi +12 more
TL;DR: It is suggested that enhanced levels of CgA identify patients with extra‐articular involvement and reveal a negative feedback loop that limits the activation of endothelial cells in RA.