R
Ruichao Li
Researcher at Yangzhou University
Publications - 66
Citations - 1453
Ruichao Li is an academic researcher from Yangzhou University. The author has contributed to research in topics: Plasmid & Escherichia coli. The author has an hindex of 14, co-authored 66 publications receiving 618 citations.
Papers
More filters
Journal ArticleDOI
Genetic characterization of mcr-1-bearing plasmids to depict molecular mechanisms underlying dissemination of the colistin resistance determinant.
Ruichao Li,Miaomiao Xie,Jinfei Zhang,Zhiqiang Yang,Lizhang Liu,Xiaobo Liu,Zhiwei Zheng,Edward Wai-Chi Chan,Sheng Chen +8 more
TL;DR: The mcr-1 gene can be disseminated via multiple mobile elements including Tn6330, its circular intermediate and plasmids harbouring such elements, and it is often co-transmitted with other resistance determinants through IncHI2 plasmsids.
Journal ArticleDOI
Antibiotic adjuvants: an alternative approach to overcome multi-drug resistant Gram-negative bacteria.
TL;DR: This review provides a brief overview of antibiotic resistance mechanism in Gram-negative bacteria, which can be used to guide the development of new antibiotic adjuvants, and summarizes the recent achievements in the search for antibiotic adjUVants based on their modes of action.
Journal ArticleDOI
Metformin Restores Tetracyclines Susceptibility against Multidrug Resistant Bacteria.
TL;DR: The antidiabetic drug metformin exhibits the potentiation effect on tetracycline antibiotics, particularly doxycycline and minocycline, against MDR S. aureus, E. coli, and S. enteritidis and boosts the immune response and alleviates the inflammatory responses in vitro.
Journal ArticleDOI
Deciphering the Structural Diversity and Classification of the Mobile Tigecycline Resistance Gene tet(X)-Bearing Plasmidome among Bacteria.
TL;DR: This study comprehensively identified and characterized the tet(X)-bearing plasmidome in different sources using advanced sequencing technologies for the first time and establishes a baseline for investigating the structure and diversity of human, animal, and environmental tigecycline resistomes.
Journal ArticleDOI
Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance.
Yuan Liu,Kangni Yang,Yuqian Jia,Jingru Shi,Ziwen Tong,Dan Fang,Bingqing Yang,Chengrui Su,Ruichao Li,Xia Xiao,Zhiqiang Wang +10 more
TL;DR: In this paper, the authors evaluated the efficacy of multiple clinically relevant bactericidal antibiotics in HFD-fed mice infected with methicillin-resistant Staphylococcus aureus (MRSA) or Escherichia coli.