R
Ruichao Li
Researcher at Yangzhou University
Publications - 66
Citations - 1453
Ruichao Li is an academic researcher from Yangzhou University. The author has contributed to research in topics: Plasmid & Escherichia coli. The author has an hindex of 14, co-authored 66 publications receiving 618 citations.
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Journal ArticleDOI
Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens.
Yuan Liu,Yuqian Jia,Kangni Yang,Ziwen Tong,Jingru Shi,Ruichao Li,Xia Xiao,Wenkai Ren,Rüdiger Hardeland,Russel J. Reiter,Zhiqiang Wang +10 more
TL;DR: Melatonin serves as a promising colistin adjuvant against MCR-positive Gram-negative pathogens and dramatically rescues colist in efficacy in three animal models infected by mcr-1-carrying E. coli.
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Drug repurposing for next-generation combination therapies against multidrug-resistant bacteria.
TL;DR: In this article, the authors provide a brief overview of the co-evolution of antibiotic discovery and the development of bacterial resistance and uncover the art of repurposing non-antibiotic drugs as potential antibiotic adjuvants.
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Emergence of IncX3 Plasmid-Harboring blaNDM-5 Dominated by Escherichia coli ST48 in a Goose Farm in Jiangsu, China.
TL;DR: The emergence of blaNDM–5-bearing strains in goose farms and the clonal transmission of E. coli within the breeding goose farm highlighted the potential reservoir of carbapenemase genes in waterfowl farming system, which may further contaminate environments and pose a threat to public health.
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Exploring tet(X)-bearing tigecycline-resistant bacteria of swine farming environments.
TL;DR: This is the first report of the emergence of IncA/C2-type plasmid-mediated tet(X6), which implies they evolved in microbiota separately, but ISCR2 should be the key element facilitating horizontal transfer of various tet( X) variants through circular intermediates.
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Anti-HIV agent azidothymidine decreases Tet(X)-mediated bacterial resistance to tigecycline in Escherichia coli.
TL;DR: It is demonstrated that anti-HIV agent azidothymidine restores tigecycline’s activity against pathogens resistant to this antibiotic.