R
Ruixin Zhu
Researcher at Tongji University
Publications - 136
Citations - 3245
Ruixin Zhu is an academic researcher from Tongji University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 25, co-authored 110 publications receiving 2119 citations. Previous affiliations of Ruixin Zhu include East China University of Science and Technology & Second Military Medical University.
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Journal ArticleDOI
Suppressed hepatic bile acid signalling despite elevated production of primary and secondary bile acids in NAFLD
Na Jiao,Susan S. Baker,Adrian Chapa-Rodriguez,Wensheng Liu,Colleen A. Nugent,Maria Tsompana,Lucy D. Mastrandrea,Michael J. Buck,Robert D. Baker,Robert J. Genco,Ruixin Zhu,Lixin Zhu +11 more
TL;DR: The serum bile acid profile, the hepatic gene expression pattern and the gut microbiome composition consistently support an elevated bile acids production in NAFLD, and suggests that future NA FLD intervention may target the components of FXR signalling, including the bile Acid converting gut microbiome.
Journal ArticleDOI
HIT: linking herbal active ingredients to targets
Hao Ye,Li Ye,Hong Kang,Duanfeng Zhang,Lin Tao,Kailin Tang,Xueping Liu,Ruixin Zhu,Qi Liu,Yu Zong Chen,Yixue Li,Zhiwei Cao +11 more
TL;DR: A comprehensive and fully curated database for Herb Ingredients’ Targets (HIT) has been constructed to complement above resources and contains 5208 entries about 1301 known protein targets affected by 586 herbal compounds from more than 1300 reputable Chinese herbs.
Proceedings ArticleDOI
Transfer Learning on Heterogenous Feature Spaces via Spectral Transformation
TL;DR: A Bayesian-based approach is applied to model the relationship between different output spaces and extracted examples from heterogeneous sources can reduce the error rate by as much as~50\%, compared with the methods using only the examples from the target task.
Journal ArticleDOI
Gut microbiome may contribute to insulin resistance and systemic inflammation in obese rodents: a meta-analysis
Na Jiao,Susan S. Baker,Colleen A. Nugent,Maria Tsompana,Liting Cai,Yong Wang,Michael J. Buck,Robert J. Genco,Robert D. Baker,Ruixin Zhu,Lixin Zhu +10 more
TL;DR: A meta-analysis of the raw sequencing data of nine studies generated from high-fat diet (HFD)-induced obese rodent models identified 15 differential taxa and 57 differential pathways between obese and lean rodents that may contribute to obesity development by promoting insulin resistance and systemic inflammation.
Journal ArticleDOI
Enteric involvement in hospitalised patients with COVID-19 outside Wuhan.
Yunle Wan,Jie Li,Lihan Shen,Yifeng Zou,Linlin Hou,Lixin Zhu,Howard Faden,Zhi-Peng Tang,Mang Shi,Na Jiao,Yichen Li,Sijing Cheng,Yibo Huang,Dingfeng Wu,Zhifeng Xu,Linnuo Pan,Jun Zhu,Guangjun Yan,Ruixin Zhu,Ping Lan +19 more