R
Ruth H. Walker
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 149
Citations - 10006
Ruth H. Walker is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Chorea & Neuroacanthocytosis. The author has an hindex of 35, co-authored 141 publications receiving 8192 citations. Previous affiliations of Ruth H. Walker include Mount Sinai Hospital & United States Department of Veterans Affairs.
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Effects of subthalamic nucleus lesions and stimulation upon glutamate levels in the dopamine-depleted rat striatum.
TL;DR: It is suggested that short-term electrical stimulation does not result in a direct inhibitory effect upon the subthalamic nucleus, and the effects of lesions differed depending upon the presence of dopamine.
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Subthalamic nucleus stimulation and lesioning have distinct state-dependent effects upon striatal dopamine metabolism.
TL;DR: It is indicated that STN stimulation and lesioning can affect striatal dopamine metabolism in the intact system, and may account for the therapeutic benefit of DBS in Parkinson's disease.
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Schizophrenia in a Patient With Spinocerebellar Ataxia 2: Coincidence of Two Disorders or a Neurodegenerative Disease Presenting With Psychosis?
TL;DR: "Clinicians should be quick to evaluate unexpected cognitive or neurological symptoms that may be interpreted mistakenly as psychiatric in origin or as side effects of neuroleptics and anticholinergic medications."
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Adolescent obsessive compulsive disorder heralding chorea-acanthocytosis.
Mark Walterfang,Mark Walterfang,Murat Yücel,Ruth H. Walker,Andrew Evans,Andrew Evans,Benedikt Bader,Ashley P. Ng,Adrian Danek,Ramon Mocellin,Ramon Mocellin,Dennis Velakoulis,Dennis Velakoulis +12 more
TL;DR: It is suggested that ChAc can be understood as a disorder whose clinical presentation reflects an interaction between the disease process and the individual's neurodevelopmental stage with both initial interrupted neurodevelopment, and supervening neurodegeneration.
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Genetic diagnosis of neuroacanthocytosis disorders using exome sequencing
Ruth H. Walker,Ruth H. Walker,Vincent P. Schulz,Irina Tikhonova,Milind Mahajan,Shrikant Mane,Maritza Arroyo Muniz,Patrick G. Gallagher +7 more
TL;DR: Exome sequencing is a valuable diagnostic tool in the neuroacanthocytosis syndromes and may provide a better understanding of the function of the associated proteins and provide insight into the pathogenesis of these disorders.