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Ryan N. Jennings

Researcher at Ohio State University

Publications -  29
Citations -  191

Ryan N. Jennings is an academic researcher from Ohio State University. The author has contributed to research in topics: Medicine & Virus. The author has an hindex of 6, co-authored 25 publications receiving 125 citations. Previous affiliations of Ryan N. Jennings include Wake Forest University.

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A Zika virus vaccine expressing premembrane-envelope-NS1 polyprotein

TL;DR: It is demonstrated that attenuated rVSV co-expressing prM, E, and NS1 is a promising vaccine candidate for protection against ZIKV infection and highlights an important role for NS1 in ZikV-specific cellular immune responses.
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Type I Interferon Signaling Enhances CD8+ T Cell Effector Function and Differentiation during Murine Gammaherpesvirus 68 Infection

TL;DR: The findings support a model in which type I IFNs likely suppress MHV68 replication, thus limiting viral antigen and facilitating an effective gammaherpesvirus-directed CD8+ T cell response.
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Phosphorylation of human metapneumovirus M2-1 protein upregulates viral replication and pathogenesis

TL;DR: It is demonstrated that phosphorylation of the M2-1 protein upregulates hMPV RNA synthesis, replication, and pathogenesis in vivo and may serve as a novel approach to develop live attenuated vaccines as well as antiviral drugs for pneumoviruses.
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Evaluation of microwave ablation for local treatment of dogs with distal radial osteosarcoma: A pilot study.

TL;DR: Microwave ablation induced variable tumor necrosis and did not induce immediate postablation complications in these six dogs with distal radius OSA, justifying further evaluation of MWA as a potential modality to treat primary bone lesions in dogs.