Ryder L. Easterlin

TL;DR: A wireless device designed to be conformally placed on the suprasternal notch can continuously provide real-time information of essential vital signs as well as talking time, swallow counts and sleep patterns.

TL;DR: Genetically adjusted PSA was more predictive of aggressive prostate cancer than unadjusted PSA and improved detection of aggressive disease when combined with a prostate cancer PGS, and it was shown that PSA-related selection bias distorts genetic associations with prostate cancer and hampers PGS performance.

TL;DR: This multi-ancestry genome-wide meta-analysis of 95,768 men discovered 128 PSA-associated variants and showed that PSA G was a more robust predictor of aggressive prostate cancer, relative to both baseline PSA and an established 269-variant prostate cancer risk score.

TL;DR: Barnea et al. as mentioned in this paper used neomers, short DNA sequences (13-17bp in length) that are largely absent from the healthy human genome, but appear in the tumor genome due to somatic mutations, to detect cancer at early stages from cfDNA.

TL;DR: In this article , the potential utility of incorporating prostate specific antigen (PSA) for personalized biomarkers in prostate cancer screening has been highlighted, showing that using PGS-adjusted PSA would avoid up to 31% of negative prostate biopsies but also result in 12% fewer biopsy in patients with prostate cancer, mostly with Gleason score <7 tumors.