R
Ryo Okubo
Researcher at Hokkaido University
Publications - 63
Citations - 567
Ryo Okubo is an academic researcher from Hokkaido University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 9, co-authored 42 publications receiving 284 citations. Previous affiliations of Ryo Okubo include Tohoku University.
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Journal ArticleDOI
Effect of bifidobacterium breve A-1 on anxiety and depressive symptoms in schizophrenia: A proof-of-concept study.
Ryo Okubo,Minori Koga,Noriko Katsumata,Toshitaka Odamaki,Shiina Matsuyama,Matsuhiko Oka,Hisashi Narita,Naoki Hashimoto,Ichiro Kusumi,Jin-zhong Xiao,Yutaka Matsuoka +10 more
TL;DR: The results suggest the potential effect of B. breve A-1 in improving anxiety and depressive symptoms in patients with schizophrenia and further studies should investigate this effect in Patients with other psychiatric conditions and assess dietary habits and the gut microbiome.
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Association of Use of Omega-3 Polyunsaturated Fatty Acids With Changes in Severity of Anxiety Symptoms: A Systematic Review and Meta-analysis.
Kuan-Pin Su,Ping-Tao Tseng,Pao-Yen Lin,Pao-Yen Lin,Ryo Okubo,Tien-Yu Chen,Tien-Yu Chen,Tien-Yu Chen,Yen-Wen Chen,Yutaka Matsuoka +9 more
TL;DR: Improvement in anxiety symptoms was associated with omega-3 polyunsaturated fatty acid treatment compared with controls in both placebo-controlled and non–placebo-controlled trials.
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Me2AlCl-mediated carboxylation, ethoxycarbonylation, and carbamoylation of indoles
Koji Nemoto,Shinya Tanaka,Megumi Konno,Satoru Onozawa,Masafumi Chiba,Yuuki Tanaka,Yoichi Sasaki,Ryo Okubo,Tetsutaro Hattori +8 more
TL;DR: In this paper, 1-methyl, 1-triisopropylsilyl-, and 1-benzylindoles are carboxylated under CO2 pressure with the aid of 1.0molar equiv of Me2AlCl to give 1-substituted indole-3-carboxylic acids in good to excellent yields.
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Increase in Social Isolation during the COVID-19 Pandemic and Its Association with Mental Health: Findings from the JACSIS 2020 Study.
TL;DR: In this paper, the authors investigated changes in the prevalence of social isolation caused by the COVID-19 pandemic and examined its association with mental health among the general Japanese population.
Journal ArticleDOI
Urbanization level and neighborhood deprivation, not COVID-19 case numbers by residence area, are associated with severe psychological distress and new-onset suicidal ideation during the COVID-19 pandemic.
Ryo Okubo,Takashi Yoshioka,Tomoki Nakaya,Tomoya Hanibuchi,Hiroki Okano,Satoru Ikezawa,Kanami Tsuno,Hiroshi Murayama,Takahiro Tabuchi +8 more
TL;DR: A nationwide, cross-sectional internet survey was conducted in Japan between August and September 2020 to examine the association between urbanization level and neighborhood deprivation as living conditions and COVID-19 case numbers by prefecture as discussed by the authors.