Ryuhei Nishino

TL;DR: Using real-time polymerase chain reaction (PCR) to measure the expression of 188 miRNAs in liver tissues obtained from 12 patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) and 14 patients with HCV-related HCC, including background liver tissues from nine patients.

TL;DR: The lipogenic pathway regulated by sterol regulatory element binding factor 1 (SREBF1) was activated in HCC and contributes to cell proliferation and prognosis and was validated by real-time RT-PCR.

TL;DR: The different signaling pathways induced in the livers of patients with CH‐B or CH‐C are described and might be useful in guiding therapeutic strategies to prevent the development of hepatocellular carcinoma in cases ofCH‐B andCH‐C.

TL;DR: Three genes are identified as specific markers of ICC: biglycan, insulin-like growth factor-binding protein 5 and claudin-4 that could be used to distinguish ICC from HCC or metastatic adenocarcinoma.

TL;DR: Proteome analysis of human hepatocellular carcinoma was done using two-dimensional difference gel electrophoresis and several proteins showed spot-to-spot differences in expression level and their expression ratios between HCC and non-HCC poorly correlated to mRNA ratios.