R
Ryuzo Fukunaga
Researcher at Osaka University
Publications - 32
Citations - 2959
Ryuzo Fukunaga is an academic researcher from Osaka University. The author has contributed to research in topics: Ischemia & Cerebral blood flow. The author has an hindex of 17, co-authored 31 publications receiving 2883 citations.
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Journal ArticleDOI
'Ischemic tolerance' phenomenon found in the brain
Kazuo Kitagawa,Masayasu Matsumoto,Masafumi Tagaya,Ryuji Hata,Hirokazu Ueda,Michio Niinobe,Nobuo Handa,Ryuzo Fukunaga,Kazufumi Kimura,Katsuhiko Mikoshiba,Takenobu Kamada +10 more
TL;DR: 'ischemic tolerance' phenomenon induced by ischemic stress--which is unquestionably important--and frequent stress in clinical medicine, is intriguing and may open a new approach to investigate the pathophysiology of isChemic neuronal damage.
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Ultrasonic evaluation of early carotid atherosclerosis.
Nobuo Handa,Masayasu Matsumoto,Hiroaki Maeda,Hidetaka Hougaku,Satoshi Ogawa,Ryuzo Fukunaga,Shotaro Yoneda,Kazufumi Kimura,Takenobu Kamada +8 more
TL;DR: High-resolution real-time B-mode ultrasonography was performed to determine the extent of atherosclerosis, and it was quantified by using a scoring system to demonstrate the clinical usefulness of high-resolution B- modes for the evaluation of early carotid Atherosclerosis.
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Microtubule-associated protein 2 as a sensitive marker for cerebral ischemic damage--immunohistochemical investigation of dendritic damage.
Kazuo Kitagawa,Masayasu Matsumoto,Michio Niinobe,Katsuhiko Mikoshiba,Ryuji Hata,Hirokazu Ueda,Nobuo Handa,Ryuzo Fukunaga,Yoshinari Isaka,Kazufumi Kimura,Takenobu Kamada +10 more
TL;DR: The present investigation suggests that dendrites in the vulnerable regions may be quite susceptible to ischemic stress and that the immunohistochemical procedure for microtubule-associated protein 2 may be very useful for demonstration of dendritic damage in various pathophysiological states of the central nervous system.
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Free radical generation during brief period of cerebral ischemia may trigger delayed neuronal death
Kazuo Kitagawa,Masayasu Matsumoto,T. Oda,Michio Niinobe,Ryuji Hata,Nobuo Handa,Ryuzo Fukunaga,Yoshinari Isaka,K. Kimura,Hiroshi Maeda,Katsuhiko Mikoshiba,Takenobu Kamada +11 more
TL;DR: The results strongly suggest that free radical generation during brief period of ischemia plays a pivotal role in triggering the ischemic neuronal damages causing delayed neuronal death at the selectively vulnerable areas of the brain.
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Hyperthermia-induced neuronal protection against ischemic injury in gerbils.
Kazuo Kitagawa,Masayasu Matsumoto,Masafumi Tagaya,Keisuke Kuwabara,Ryuji Hata,Nobuo Handa,Ryuzo Fukunaga,Kazufumi Kimura,Takenobu Kamada +8 more
TL;DR: This transient and cumulative neuroprotective effect of hyperthermic pretreatment strongly suggested the involvement of stress reactions after hyperthermia in the protective mechanism against ischemic neuronal death.