S
Sae-Kwang Ku
Researcher at Daegu Haany University
Publications - 496
Citations - 10676
Sae-Kwang Ku is an academic researcher from Daegu Haany University. The author has contributed to research in topics: Tumor necrosis factor alpha & Inflammation. The author has an hindex of 45, co-authored 468 publications receiving 8295 citations.
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Gel characterisation and in vivo evaluation of minocycline-loaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan.
Jung Hoon Sung,Ma-Ro Hwang,Jong Oh Kim,Jeong Hoon Lee,Yong-Il Kim,Jeong Hoon Kim,Sun Woo Chang,Sung Giu Jin,Jung-Ae Kim,Won Seok Lyoo,Sung Soo Han,Sae-Kwang Ku,Chul Soon Yong,Han-Gon Choi +13 more
TL;DR: In wound healing test, this minocycline-loaded PVA-chitosan hydrogel showed faster healing of the wound made in rat dorsum than the conventional product or the control (sterile gauze) due to antifungal activity of chitOSan.
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NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1α
Tae-Hyoung Kim,Eu-gene Hur,Su-Jin Kang,Jung-Ae Kim,Dinesh Thapa,You Mie Lee,Sae-Kwang Ku,Yunjin Jung,Mi-Kyoung Kwak +8 more
TL;DR: Novel insights are offered into how cellular responses to O(2) and oxidative stress are integrated in cancer cells, and NRF2 is highlighted as a candidate molecular target to control tumor angiogenesis by imposing a blockade to HIF-1α signaling.
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Anti-inflammatory Effects of Baicalin, Baicalein, and Wogonin In Vitro and In Vivo
TL;DR: It is suggested that baicalin, baicalein, and wogonin posses anti-inflammatory functions by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases.
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Gentamicin-Loaded Wound Dressing With Polyvinyl Alcohol/Dextran Hydrogel: Gel Characterization and In Vivo Healing Evaluation
Ma-Ro Hwang,Jong Oh Kim,Jeong Hoon Lee,Yong-Il Kim,Jeong Hoon Kim,Sun Woo Chang,Sung Gju Jin,Jung-Ae Kim,Won Seok Lyoo,Sung Soo Han,Sae-Kwang Ku,Chul Soon Yong,Han-Gon Choi +12 more
TL;DR: From the in vivo wound healing and histological results, this gentamicin-loaded wound dressing enhanced the healing effect more compared to conventional product because of the potential healing effect of gentamicino, which is used as a potential wound dressing with excellent forming and improved healing effect in wound care.
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Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy
Wenquan Ou,Raj Kumar Thapa,Liyuan Jiang,Zar Chi Soe,Milan Gautam,Jae-Hoon Chang,Jee-Heon Jeong,Sae-Kwang Ku,Han-Gon Choi,Chul Soon Yong,Jong Oh Kim +10 more
TL;DR: The tLyp1 peptide‐modified hybrid nanoparticles presented good stability and effective targeting to Treg cells, and they enhanced the effect of imatinib in downregulating Treg cell suppression through inhibition of STAT3 and STAT5 phosphorylation.