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Sae-Kwang Ku

Researcher at Daegu Haany University

Publications -  496
Citations -  10676

Sae-Kwang Ku is an academic researcher from Daegu Haany University. The author has contributed to research in topics: Tumor necrosis factor alpha & Inflammation. The author has an hindex of 45, co-authored 468 publications receiving 8295 citations.

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Gel characterisation and in vivo evaluation of minocycline-loaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan.

TL;DR: In wound healing test, this minocycline-loaded PVA-chitosan hydrogel showed faster healing of the wound made in rat dorsum than the conventional product or the control (sterile gauze) due to antifungal activity of chitOSan.
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NRF2 Blockade Suppresses Colon Tumor Angiogenesis by Inhibiting Hypoxia-Induced Activation of HIF-1α

TL;DR: Novel insights are offered into how cellular responses to O(2) and oxidative stress are integrated in cancer cells, and NRF2 is highlighted as a candidate molecular target to control tumor angiogenesis by imposing a blockade to HIF-1α signaling.
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Anti-inflammatory Effects of Baicalin, Baicalein, and Wogonin In Vitro and In Vivo

TL;DR: It is suggested that baicalin, baicalein, and wogonin posses anti-inflammatory functions by inhibiting hyperpermeability, expression of CAMs, and adhesion and migration of leukocytes, thereby endorsing its usefulness as a therapy for vascular inflammatory diseases.
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Gentamicin-Loaded Wound Dressing With Polyvinyl Alcohol/Dextran Hydrogel: Gel Characterization and In Vivo Healing Evaluation

TL;DR: From the in vivo wound healing and histological results, this gentamicin-loaded wound dressing enhanced the healing effect more compared to conventional product because of the potential healing effect of gentamicino, which is used as a potential wound dressing with excellent forming and improved healing effect in wound care.
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Regulatory T cell-targeted hybrid nanoparticles combined with immuno-checkpoint blockage for cancer immunotherapy

TL;DR: The tLyp1 peptide‐modified hybrid nanoparticles presented good stability and effective targeting to Treg cells, and they enhanced the effect of imatinib in downregulating Treg cell suppression through inhibition of STAT3 and STAT5 phosphorylation.