S
Sally Pinz-Sweeney
Researcher at Scripps Research Institute
Publications - 1
Citations - 578
Sally Pinz-Sweeney is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Phage display & Affinity maturation. The author has an hindex of 1, co-authored 1 publications receiving 569 citations.
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CDR Walking Mutagenesis for the Affinity Maturation of a Potent Human Anti-HIV-1 Antibody into the Picomolar Range
Wei-Ping Yang,Kimberly Green,Sally Pinz-Sweeney,Amelia T. Briones,Dennis R. Burton,Carlos F. Barbas +5 more
TL;DR: The methodology presented here provides a route for the improvement of the affinities of antibodies typical of tertiary immune responses into the picomolar range and may have profound effects on the utility of antibodies as therapeutic and prophylactic agents.