S
Sally Rastani
Researcher at Wake Forest University
Publications - 1
Citations - 651
Sally Rastani is an academic researcher from Wake Forest University. The author has contributed to research in topics: Phosphorylation & Downregulation and upregulation. The author has an hindex of 1, co-authored 1 publications receiving 629 citations.
Papers
More filters
Journal ArticleDOI
Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase perk and phosphorylation of the translation initiation factor eif2alpha
Constantinos Koumenis,Christine Naczki,Marianne Koritzinsky,Sally Rastani,Alan J. Diehl,Nahum Sonenberg,Antonis E. Koromilas,Bradly G. Wouters +7 more
TL;DR: Results indicate that adaptation of cells to hypoxic stress requires activation of PERK and phosphorylation of eIF2α and suggest that the mechanism of hypoxia-induced translational attenuation may be linked to ER stress and the unfolded-protein response.