Salvatore De Vita

TL;DR: Rituximab may represent a safe and effective alternative to standard immunosuppression in type II MC and is effective on skin vasculitis manifestations, subjective symptoms of peripheral neuropathy, low-grade B-cell lymphoma, arthralgias, and fever.

TL;DR: The finding of the clinical efficacy of selective B cell blockade indicates that B cells play a critical role in rheumatoid synovitis, at least in a subset of patients.

TL;DR: Encouraging results justify future randomised controlled trials of belimumab in a selected target population of pSS patients most likely to benefit from treatment.

TL;DR: Analysis of the immunoglobulin receptor (IGR) variable heavy- and light-chain sequences on 17 hepatitis C virus-associated non-Hodgkin lymphomas suggest that such malignant lymphoproliferations derive from an antigen-driven pathologic process, with a selective pressure for the maintenance of a functional IgR and a negative pressure for additional amino acid mutations in the framework regions (FRs).

TL;DR: A user guide for the ESSDAI is provided, which provides definitions and precisions on the rating of each domain, and includes some minor improvement of the score to integrate advance in knowledge of disease manifestations.