S
Sam Dawkins
Researcher at University of Oxford
Publications - 28
Citations - 552
Sam Dawkins is an academic researcher from University of Oxford. The author has contributed to research in topics: Myocardial infarction & Percutaneous coronary intervention. The author has an hindex of 9, co-authored 25 publications receiving 331 citations. Previous affiliations of Sam Dawkins include National Institute for Health Research & Cedars-Sinai Medical Center.
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Journal ArticleDOI
How does coronary stent implantation impact on the status of the microcirculation during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction?
Giovanni Luigi De Maria,Florim Cuculi,Niket Patel,Sam Dawkins,Gregor Fahrni,George Kassimis,Robin P. Choudhury,J C Forfar,Bernard Prendergast,Keith M. Channon,Rajesh K. Kharbanda,Adrian P. Banning +11 more
TL;DR: Improved perfusion of the myocardium by stent deployment during PPCI is not universal, and the causes of impaired microvascular function at the completion of PPCi treatment are heterogeneous, but can reflect a later clinical presentation and/or the location and extent of the thrombotic burden.
Journal ArticleDOI
Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction.
Naveed Akbar,J Digby,Thomas J. Cahill,A N Tavare,Alastair L. Corbin,S Saluja,Sam Dawkins,Laurienne Edgar,Nadiia Rawlings,Klemen Ziberna,Eileen McNeill,Errin Johnson,Alaa A. A. Aljabali,R Dragovic,Mala Rohling,T G Belgard,Irina A. Udalova,David R. Greaves,Keith M. Channon,Paul R. Riley,Daniel C. Anthony,Robin P. Choudhury +21 more
TL;DR: Findings identify EVs as a possible novel signaling pathway by linking ischemic myocardium with monocyte mobilization and transcriptional activation following AMI by identifying EVs as the most enriched pathway for the miRNA-mRNA targets.
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CMR Native T1 Mapping Allows Differentiation of Reversible Versus Irreversible Myocardial Damage in ST-Segment-Elevation Myocardial Infarction: An OxAMI Study (Oxford Acute Myocardial Infarction).
Dan Liu,Alessandra Borlotti,Dafne Viliani,Michael Jerosch-Herold,Mohammad Alkhalil,Giovanni Luigi De Maria,Gregor Fahrni,Sam Dawkins,Rohan S. Wijesurendra,Jane E. Francis,Vanessa M Ferreira,Stefan K. Piechnik,Matthew D. Robson,Adrian P. Banning,Robin P. Choudhury,Stefan Neubauer,Keith M. Channon,Rajesh K. Kharbanda,Erica Dall'Armellina +18 more
TL;DR: In this paper, CMR T1 mapping is used to assess myocardial injury early after ST-segment-elevation myocardious infarction, and the authors investigated the abili...
Journal ArticleDOI
Index of Microcirculatory Resistance as a Tool to Characterize Microvascular Obstruction and to Predict Infarct Size Regression in Patients With STEMI Undergoing Primary PCI.
Giovanni Luigi De Maria,Mohammad Alkhalil,Mathias Wolfrum,Gregor Fahrni,Alessandra Borlotti,L Gaughran,Sam Dawkins,Jeremy P Langrish,Andrew J. Lucking,Robin P. Choudhury,Italo Porto,Filippo Crea,Erica Dall'Armellina,Keith M. Channon,Rajesh K. Kharbanda,Adrian P. Banning,Adrian P. Banning +16 more
TL;DR: Discordant prognostic information was obtained from IMR and MVO in nearly one-third of cases; however, IMR can be helpful in grading the degree and severity of MVO.
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Zero-Flow Pressure Measured Immediately After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Provides the Best Invasive Index for Predicting the Extent of Myocardial Infarction at 6 Months: An OxAMI Study (Oxford Acute Myocardial Infarction)
Niket Patel,Ricardo Petraco,Erica Dall'Armellina,George Kassimis,Giovanni Luigi De Maria,Sam Dawkins,Regent Lee,Bernard Prendergast,Robin P. Choudhury,J C Forfar,Keith M. Channon,Justin E. Davies,Adrian P. Banning,Rajesh K. Kharbanda +13 more
TL;DR: Pzf measured at the time of PPCI is a better predictor of the extent of myocardial infarction than hMR or IMR and merits further investigation in clinical studies with relevant outcome measures.