G
George Kassimis
Researcher at Aristotle University of Thessaloniki
Publications - 101
Citations - 1380
George Kassimis is an academic researcher from Aristotle University of Thessaloniki. The author has contributed to research in topics: Percutaneous coronary intervention & Medicine. The author has an hindex of 13, co-authored 75 publications receiving 1123 citations. Previous affiliations of George Kassimis include Gloucestershire Hospitals NHS Foundation Trust & Cheltenham General Hospital.
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Journal ArticleDOI
Randomized Assessment of Ticagrelor Versus Prasugrel Antiplatelet Effects in Patients with ST-Segment–Elevation Myocardial Infarction
Dimitrios Alexopoulos,Ioanna Xanthopoulou,Vassilios Gkizas,George Kassimis,Konstantinos Theodoropoulos,George Makris,Nikolaos Koutsogiannis,Anastasia Damelou,Grigorios Tsigkas,Periklis Davlouros,George Hahalis +10 more
TL;DR: In patients with ST-segment–elevation myocardial infarction undergoing primary percutaneous coronary intervention, both ticagrelor and prasugrel exhibit an initial delay in the onset of their antiplatelet action.
Journal ArticleDOI
Ticagrelor versus prasugrel in acute coronary syndrome patients with high on-clopidogrel platelet reactivity following percutaneous coronary intervention: a pharmacodynamic study.
Dimitrios Alexopoulos,Anastasia Galati,Ioanna Xanthopoulou,Eleni Mavronasiou,George Kassimis,Konstantinos Theodoropoulos,George Makris,Anastasia Damelou,Grigorios Tsigkas,George Hahalis,Periklis Davlouros +10 more
TL;DR: In patients with ACS exhibiting HTPR while on clopidogrel 24 h post-PCI, ticagrelor produces a significantly higher platelet inhibition compared with prasugrel.
Journal ArticleDOI
Prasugrel overcomes high on-clopidogrel platelet reactivity post-stenting more effectively than high-dose (150-mg) clopidogrel: the importance of CYP2C19*2 genotyping
Dimitrios Alexopoulos,Gerasimos Dimitropoulos,Periklis Davlouros,Ioanna Xanthopoulou,George Kassimis,Eleana F. Stavrou,George Hahalis,Aglaia Athanassiadou +7 more
TL;DR: In patients with HTPR after PCI, prasugrel is more effective compared with high clopidogrel in reducing platelet reactivity, particularly in CYP2C19*2 carriers.
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How does coronary stent implantation impact on the status of the microcirculation during primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction?
Giovanni Luigi De Maria,Florim Cuculi,Niket Patel,Sam Dawkins,Gregor Fahrni,George Kassimis,Robin P. Choudhury,J C Forfar,Bernard Prendergast,Keith M. Channon,Rajesh K. Kharbanda,Adrian P. Banning +11 more
TL;DR: Improved perfusion of the myocardium by stent deployment during PPCI is not universal, and the causes of impaired microvascular function at the completion of PPCi treatment are heterogeneous, but can reflect a later clinical presentation and/or the location and extent of the thrombotic burden.
Journal ArticleDOI
Zero-Flow Pressure Measured Immediately After Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Provides the Best Invasive Index for Predicting the Extent of Myocardial Infarction at 6 Months: An OxAMI Study (Oxford Acute Myocardial Infarction)
Niket Patel,Ricardo Petraco,Erica Dall'Armellina,George Kassimis,Giovanni Luigi De Maria,Sam Dawkins,Regent Lee,Bernard Prendergast,Robin P. Choudhury,J C Forfar,Keith M. Channon,Justin E. Davies,Adrian P. Banning,Rajesh K. Kharbanda +13 more
TL;DR: Pzf measured at the time of PPCI is a better predictor of the extent of myocardial infarction than hMR or IMR and merits further investigation in clinical studies with relevant outcome measures.