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Samantha M. Kimball

Researcher at University of Calgary

Publications -  34
Citations -  2116

Samantha M. Kimball is an academic researcher from University of Calgary. The author has contributed to research in topics: Vitamin D and neurology & Vitamin. The author has an hindex of 19, co-authored 33 publications receiving 1825 citations. Previous affiliations of Samantha M. Kimball include Mount Sinai Hospital, Toronto & Saint Mary's University.

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A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis

TL;DR: This trial provides Class II evidence that high-dose vitamin D use for 52 weeks in patients with multiple sclerosis does not significantly increase serum calcium levels when compared to patients not on high- doses, with evidence of immunomodulatory effects.
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Safety of vitamin D3 in adults with multiple sclerosis

TL;DR: Patients' serum 25(OH)D concentrations reached twice the top of the physiologic range without eliciting hypercalcemia or hypercalciuria, providing objective evidence that vitamin D intake beyond the current upper limit is safe by a large margin.
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Randomized comparison of the effects of the vitamin D 3 adequate intake versus 100 mcg (4000 IU) per day on biochemical responses and the wellbeing of patients

TL;DR: The highest AI for vitamin D brought summertime 25(OH)D to >40 nmol/L, lowered PTH, and its use was associated with improved wellbeing, confirming the safety and efficacy of both 15 and 100 mcg/day vitamin D3 in patients who needed additional vitamin D.
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Short- and long-term safety of weekly high-dose vitamin D3 supplementation in school children.

TL;DR: Vitamin D(3) at doses equivalent to 2000 IU/d for 1 yr is safe in adolescents and results in desirable vitamin D levels.