S
Samuele Vannini
Researcher at University of Perugia
Publications - 26
Citations - 387
Samuele Vannini is an academic researcher from University of Perugia. The author has contributed to research in topics: Genotoxicity & Comet assay. The author has an hindex of 11, co-authored 26 publications receiving 299 citations.
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Journal ArticleDOI
Occupational exposure to cytostatic/antineoplastic drugs and cytogenetic damage measured using the lymphocyte cytokinesis-block micronucleus assay: A systematic review of the literature and meta-analysis.
Milena Villarini,Vincenza Gianfredi,Sara Levorato,Samuele Vannini,Tania Salvatori,Massimo Moretti +5 more
TL;DR: The meta-analysis of MN frequency of the combined studies confirmed an association between occupational exposure to ANPD and cytogenetic effects with an overall meta-estimate of 1.67 [95% CI: 1.41-1.98].
Journal ArticleDOI
Investigation of the Cytotoxic, Genotoxic, and Apoptosis-Inducing Effects of Estragole Isolated from Fennel (Foeniculum vulgare)
Milena Villarini,Rita Pagiotti,Luca Dominici,Cristina Fatigoni,Samuele Vannini,Sara Levorato,Sara Levorato,Massimo Moretti +7 more
TL;DR: The comet assay indicated that estragole was not able to induce DNA damage nor apoptosis under the experimental conditions used, and potential genotoxic effects, including DNA damage and apoptosis were indicated.
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Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis
Vincenza Gianfredi,Samuele Vannini,Massimo Moretti,Milena Villarini,Nicola Luigi Bragazzi,Alberto Izzotti,Daniele Nucci +6 more
TL;DR: Beneficial effects of dietary bioactive compounds such as SFN and EGCG and their effect on BC cells are suggested by restoring estrogen receptor gene expression, modulating epigenetic changes and events, and interfering with tumor growth rate.
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In Vitro Protective Effects of Lycium barbarum Berries Cultivated in Umbria (Italy) on Human Hepatocellular Carcinoma Cells
Maria Rachele Ceccarini,Samuele Vannini,Samuela Cataldi,Massimo Moretti,Milena Villarini,Bernard Fioretti,Elisabetta Albi,Tommaso Beccari,Michela Codini +8 more
TL;DR: It was demonstrated, for the first time, that the berries extract showed a protective effect on DNA damage, expressed as antigenotoxic activity in vitro, and Lycium barbarum berries extract was able to modulate the expression of genes involved in oxidative stress, proliferation, apoptosis, and cancer.
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Buccal micronucleus cytome assay in primary school children: A descriptive analysis of the MAPEC_LIFE multicenter cohort study.
Milena Villarini,Sara Levorato,Tania Salvatori,Elisabetta Ceretti,Sara Bonetta,Annalaura Carducci,Tiziana Grassi,Samuele Vannini,Francesco Donato,Silvia Bonetta,Marco Verani,Antonella De Donno,S. Bonizzoni,A. Bonetti,Massimo Moretti,Umberto Gelatti,Cristina Fatigoni,Silvano Monarca,Loredana Covolo,Donatella Feretti,Andrea Festa,Gaia Claudia Viviana Viola,Claudia Zani,Ilaria Zerbini,Giorgio Gilli,Elisabetta Carraro,Tiziana Schilirò,Cristina Pignata,Marta Gea,Valeria Romanazzi,Gabriele Donzelli,G. Palomba,Francesco Bagordo,Mattia De Giorgi,Marcello Guido,Adele Idolo,Alessandra Panico,Francesca Di Serio,Tiziano Verri,Camilla Furia,Paolo Colombi,Roberta Codenotti,Licia Zagni +42 more
TL;DR: MN frequency was associated with winter season and living in towns at various levels of air pollution, suggesting an important role of this exposure in determining early cytogenetic effects.