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Showing papers by "Samy M. El-Megharbel published in 2019"

Journal Article•DOI•
Synthesis of new antidiabetic agent by complexity between vanadyl (II) sulfate and vitamin B1: Structural, characterization, anti‐DNA damage, structural alterations and antioxidative damage studies

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Samy M. El-Megharbel1, Samy M. El-Megharbel2, Reham Z. Hamza2, Reham Z. Hamza1, Adil A. Gobouri2, Moamen S. Refat3, Moamen S. Refat2 •
Zagazig University1, Taif University2, Port Said University3
01 May 2019-Applied Organometallic Chemistry

11 citations

Journal Article•DOI•
Synthesis, Spectroscopy, and Anticancer Activity of Two New Nanoscale Au(III) N 4 Schiff Base Complexes

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Ahmed M. Naglah1, Mohamed A. Al-Omar1, Atef Kalmouch, Adel A. Gobouri2, Shams H. Abdel-Hafez3, Shams H. Abdel-Hafez2, Samy M. El-Megharbel4, Samy M. El-Megharbel2, Moamen S. Refat2, Moamen S. Refat5 •
King Saud University1, Taif University2, Assiut University3, Zagazig University4, Port Said University5
01 Aug 2019-Russian Journal of General Chemistry
TL;DR: In this paper, the chemical structures of new Schiff bases and their Au(III) complexes are elucidated from their conductance, XRD, and spectroscopic (IR, UV-Vis, 1H, and 13C NMR) data.
Abstract: Mononuclear Au(III) Schiff base complexes are synthesized by the reaction of 4-aminoantipyrine with hydrazine. The chemical structures of new Schiff bases and their Au(III) complexes are elucidated from their conductance, XRD, and spectroscopic (IR, UV-Vis, 1H, and 13C NMR) data. Au(III) Ion is coordinated with the synthesized Schiff bases via four nitrogen atoms of the antipyrine and azomethine groups. Au(III) Complexes are electrolytes with three uncoordinated Cl− ions, and have a square planar geometry. Their morphology is characterized by SEM and TEM methods. Cytotoxic effect of the complexes is tested against human breast cancer (MCF-7) and hepatocellular carcinoma (HepG-2) cell lines.

7 citations