M
Mohamed A. Al-Omar
Researcher at King Saud University
Publications - 300
Citations - 3736
Mohamed A. Al-Omar is an academic researcher from King Saud University. The author has contributed to research in topics: Pyridine & Chemistry. The author has an hindex of 26, co-authored 289 publications receiving 3034 citations. Previous affiliations of Mohamed A. Al-Omar include Ain Shams University & University of Western Ontario.
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Journal ArticleDOI
Synthesis, antimicrobial, and anti-HIV-1 activity of certain 5-(1-adamantyl)-2-substituted thio-1,3,4-oxadiazoles and 5-(1-adamantyl)-3-substituted aminomethyl-1,3,4-oxadiazoline-2-thiones
TL;DR: Compounds 2, 5a, and 5e were found as the most active derivatives, particularly against the Gram-positive bacteria and the yeast-like pathogenic fungus Candida albicans.
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Design, synthesis and biological evaluation of novel quinazoline derivatives as potential antitumor agents: Molecular docking study
Adel S. El-Azab,Mohamed A. Al-Omar,Alaa A.-M. Abdel-Aziz,Naglaa I. Abdel-Aziz,Magda A.-A. El-Sayed,Abdulaziz M. Aleisa,Mohamed M. Sayed-Ahmed,Sami G. Abdel-Hamide +7 more
TL;DR: Novel derivatives of quinazoline have been synthesized and tested for their antitumor activity against three tumor cell lines among these cell lines the human breast carcinoma cell line (MCF-7) in which EGFR is highly expressed.
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Non-classical antifolates. Part 2: Synthesis, biological evaluation, and molecular modeling study of some new 2,6-substituted-quinazolin-4-ones
Fatmah A.M. Al-Omary,Laila A. Abou-Zeid,Mahmoud N. Nagi,El-Sayed E. Habib,Alaa A.-M. Abdel-Aziz,Adel S. El-Azab,Sami G. Abdel-Hamide,Mohamed A. Al-Omar,Abdulrahman M. Al-Obaid,Hussein I. El-Subbagh +9 more
TL;DR: A new series of 2,6-substituted-quinazolin-4-ones was designed, synthesized, and evaluated for their in vitro DHFR inhibition, antimicrobial, and antitumor activities and proved critical for biological activity.
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Ureteroscopy for pediatric urolithiasis: An evolving first-line therapy
TL;DR: Ureteroscopy is safe and effective in the management of ureteral and renal calculi in children and has emerged as a valid first-line therapy for the treatment of pediatric urolithiasis.
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Synthesis and antimicrobial activity of novel 5-(1-adamantyl)-2-aminomethyl-4-substituted-1,2,4-triazoline-3-thiones.
Ali A. El-Emam,Abdul-Malek S. Al-Tamimi,Mohamed A. Al-Omar,Khalid A. Al-Rashood,El-Sayed E. Habib +4 more
TL;DR: The reaction of 5-(1-adamantyl)-4-substituted-1,2,4-triazoline-3-thione with formaldehyde solution yielded the corresponding N-Mannich bases 6a-o, 7a-g and 11a-i, which were tested for in vitro inhibitory activities against a panel of Gram-positive and Gram-negative bacteria and the yeast-like pathogenic fungus Candida albicans.